72647-96-2 Usage
Description
4-Nitrophenyl 6-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside, with the CAS number 72647-96-2, is a white solid compound that is primarily utilized in the field of organic synthesis. It is a derivative of a disaccharide, consisting of two sugar units connected through a glycosidic bond. 4-Nitrophenyl 6-O-(a-D-Mannopyranosyl)-a-D-mannopyranoside is characterized by the presence of a nitrophenyl group and a mannopyranosyl unit, which contribute to its unique chemical properties and potential applications.
Uses
1. Used in Organic Synthesis:
4-Nitrophenyl 6-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside is used as a synthetic intermediate for the preparation of various complex organic molecules, particularly those involving carbohydrate moieties. Its unique structure allows for the selective functionalization and modification of the sugar units, making it a valuable building block in the synthesis of bioactive compounds, pharmaceuticals, and other specialty chemicals.
2. Used in Glycobiology and Glycochemistry Research:
In the field of glycobiology, which focuses on the study of carbohydrates and their interactions with biological systems, 4-Nitrophenyl 6-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside serves as a model compound for understanding the structure, function, and recognition of glycans. It can be used to investigate the specificity of glycosidases, lectins, and other carbohydrate-binding proteins, as well as to study the role of glycans in cellular processes and disease mechanisms.
3. Used in Analytical Chemistry and Assay Development:
4-Nitrophenyl 6-O-(a-D-Mannopyranosyl)-a-D-mannopyranoside can be employed as a substrate or standard in the development and optimization of analytical methods for the detection and quantification of carbohydrates and their derivatives. Its distinct chemical properties make it suitable for use in high-performance liquid chromatography (HPLC), mass spectrometry, and other analytical techniques, allowing for the accurate determination of carbohydrate-related compounds in various samples.
4. Used in Drug Discovery and Development:
Due to its unique structure and potential biological activities, 4-Nitrophenyl 6-O-(α-D-Mannopyranosyl)-α-D-mannopyranoside may also be explored for its potential therapeutic applications. It could serve as a lead compound in the development of new drugs targeting carbohydrate-related diseases, such as diabetes, cancer, and infectious diseases, where glycans play a crucial role in pathogenesis and host-pathogen interactions.
5. Used in Material Science:
4-Nitrophenyl 6-O-(a-D-Mannopyranosyl)-a-D-mannopyranoside's chemical properties and structural features may also find applications in the field of material science, particularly in the development of carbohydrate-based materials with specific properties, such as hydrogels, coatings, and films. These materials could have potential applications in various industries, including pharmaceuticals, food, and cosmetics, where tailored properties and functionalities are desired.
Check Digit Verification of cas no
The CAS Registry Mumber 72647-96-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,6,4 and 7 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 72647-96:
(7*7)+(6*2)+(5*6)+(4*4)+(3*7)+(2*9)+(1*6)=152
152 % 10 = 2
So 72647-96-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H25NO13/c20-5-9-11(21)13(23)15(25)17(31-9)29-6-10-12(22)14(24)16(26)18(32-10)30-8-3-1-7(2-4-8)19(27)28/h1-4,9-18,20-26H,5-6H2/t9-,10-,11-,12-,13+,14+,15+,16+,17+,18+/m1/s1
72647-96-2Relevant articles and documents
Isolation and characterization of a novel α-glucosidase with transglycosylation activity from Arthrobacter sp. DL001
Zhou, Kun,Luan, Hong-Wei,Hu, Ying,Ge, Guang-Bo,Liu, Xing-Bao,Ma, Xiao-Chi,Hou, Jie,Wang, Xiu-Li,Yang, Ling
experimental part, p. 48 - 57 (2012/09/07)
A strain of Arthrobacter sp. DL001 with high transglycosylation activity was successfully isolated from the Yellow Sea of China. To purify the extracellular enzyme responsible for transglycosylation, a four-step protocol was adopted and the enzyme with electrophoretical purity was obtained. The purified enzyme has a molecular mass of 210 kDa and displays a narrow hydrolysis specificity towards α-1,4-glucosidic bond. Its hydrolytic activity was identified as decreasing in the order of maltotriose > panose > maltose. Only 3.61% maltose activity occurs when p-nitrophenyl α-d-glycopyranoside serves as a substrate, suggesting that this enzyme belongs to the type II α-glucosidase. In addition, the enzyme was able to transfer glucosyl groups from the donors containing α-1,4-glucosidic bond specific to glucosides, xylosides and alkyl alcohols in α-1,4- or α-1,6-manners. A decreased order of activity was observed when maltose, maltotriose, panose, β-cyclodextrin and soluble starch served as glycosyl donors, respectively. When maltose was utilized as a donor and a series of p-nitrophenyl-glycosides as acceptors, the glucosidase was capable of transferring glucosyl groups to p-nitrophenyl-glucosides and p-nitrophenyl-xylosides in α-1,4- or α-1,6-manners. The yields of p-nitrophenyl-oligosaccharides could reach 42-60% in 2 h. When a series of alkyl alcohols were utilized as acceptors, the enzyme exhibited its transglycosylation activities not only to the primary alcohols but also to the secondary alcohols with carbon chain length 1-4. Therefore, all the results indicated that the purified α-glucosidase present a useful tool for the biosynthesis of oligosaccharides and alkyl glucosides.
Enzymic synthesis of p-nitrophenyl α-glucobiosides by use of native and immobilized rice α-glucosidase
Asano, Naoki,Tanaka, Ken,Matsui, Katsuhiko
, p. 255 - 262 (2007/10/02)
-
