72656-48-5

Basic information

• Product Name: Benzenepropanoic acid, b-hydroxy-, 1,1-dimethylethyl ester, (R)-
• CAS NO: 72656-48-5
• Molecular Formula: C13H18O3
• Molecular Weight: 222.284
• Mol File: 72656-48-5.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, b-hydroxy-, 1,1-dimethylethyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, b-hydroxy-, 1,1-dimethylethyl ester, (R)-(72656-48-5)
• EPA Substance Registry System: Benzenepropanoic acid, b-hydroxy-, 1,1-dimethylethyl ester, (R)-(72656-48-5)

Safety Data

• Hazardous Substances Data: 72656-48-5(Hazardous Substances Data)

Upstream product

• 54441-66-6 tert-butyl benzoylacetate 
• 14990-09-1 tert-butyl cinnamate 
• 5397-27-3 tert-butyl 3-hydroxy-3-phenylpropionate 
• 22651-87-2 cyclohexanecarboxylic acid anhydride 
• 1760-46-9 diphenylacetic anhydride 
• 108-24-7 acetic anhydride 
• 49827-15-8 t-butyl iodoacetate 
• 100-52-7 benzaldehyde 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 58059-08-8 tert-butyl (R)-p-toluenesulfinylacetate 
• 139223-54-4 (S_(S)R)-tert-butyl o-<1-(tert-butylcarbonylamino)ethyl>phenylsulfinylacetate 
• 63006-68-8 tert-butyl (phenylthio)acetate 
• 540-88-5 acetic acid tert-butyl ester 
• 74786-02-0 1-(tert-butyldimethylsilyloxy)-1-tert-butoxyethylene 

Downstream Products

• 103548-16-9 (R)-3-phenyl-1,3-dihydroxypropane 

Relevant articles and documents

On the basis of the phenethylamine skeleton chiral P, N, N ligand compound and its manufacturing method and application (by machine translation)

The present invention provides a chiral P based on the skeleton of the phenethylamine, N, N ligand compound and its manufacturing method and application, surfactant-ethylamine skeleton chiral P, N, N ligand compound of preparation method is as follows: under the protection of nitrogen, the chiral phenylethylamine - [...] compound with 2 - chloromethyl oxazole oxazoline compounds soluble in the reaction solvent, adding alkali, reflux reaction, filtering, desolvation, column chromatography to obtain the required chiral P, N, N ligand compound. In particular to the β - ketoacid ester compound in asymmetric catalytic hydrogenation reaction. The invention of the phenethylamine skeleton chiral P, N, β - keto ester N ligand can be applied to the asymmetric catalytic hydrogenation reaction, can be high yield and high enantio-selectively for the preparation of chiral β - hydroxy ester. (by machine translation)

Efficient P-Chiral Biaryl Bisphosphorus Ligands for Palladium-Catalyzed Asymmetric Hydrogenation

A series of structurally novel P-chiral biaryl bisphosphorus ligands L1-L5 (BABIBOPs) are developed, providing high efficiency for the first time in palladium-catalyzed asymmetric hydrogenation of β-aryl and β-alkyl substituted β-keto esters. With the Pd-L3 (iPr-BABIBOP) catalyst, a series of chiral β-hydroxyl carboxylic esters are formed in excellent enantioselectivities (up to>99% ee) and yields at catalyst loading as low as 0.01 mol%.

PLANAR CHIRAL METALLOCENE RING-FUSED CARBENE AND PRODUCTION METHOD THEREFOR, AND METAL COMPLEX WITH THE DERIVATIVE AS LIGAND

PROBLEM TO BE SOLVED: To provide a planar chiral carbene ligand which is easily synthesized. SOLUTION: There is provided a carbene which can be synthesized from a planar chiral iminium salt derivative of the formula (1), where R1 to R9 are H, a substituted/unsubstituted C1 to C20 hydrocarbon group, a substituted/unsubstituted C1 to C20 alkoxy group, a substituted/unsubstituted C6 to C20 aryloxy group, a substituted/unsubstituted amino group, a substituted/unsubstituted phosphino group, a substituted/unsubstituted silyl group, a substituted/unsubstituted alkylthio group or a substituted/unsubstituted arylthio group or the like; X is a substituted/unsubstituted C1 to C4 carbon atom or a substituted/unsubstituted atomic group consisting of N, O, S or any combination of these hetero atoms and a carbon atom which may have a substituent; Z is a halogen atom, PF6, BF4, ClO4 or BPh4; and M is a transition atom such as Fe and Ru. Although the formula (1) represents one of two enantiomers of planar chiral compound, it may be another enantiomer. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT