72658-10-7 Usage
Description
(1E)-1-tert-Butoxy-1-(trimethylsilyloxy)propene, also known as tert-butoxy(trimethylsilyloxy)propene, is a chemical compound with the molecular formula C9H20OSi. It is a colorless liquid that is often used as a reagent in organic synthesis reactions. (1E)-1-tert-Butoxy-1-(trimethylsilyloxy)propene is known for its ability to undergo addition and substitution reactions, making it a valuable asset in the preparation of various organic compounds.
Uses
Used in Organic Synthesis:
(1E)-1-tert-Butoxy-1-(trimethylsilyloxy)propene is used as a reagent in organic synthesis for its ability to undergo addition and substitution reactions. This allows for the creation of a wide range of organic compounds, making it a versatile tool in the field of chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1E)-1-tert-Butoxy-1-(trimethylsilyloxy)propene is used as an intermediate in the synthesis of various pharmaceuticals. Its ability to participate in addition and substitution reactions aids in the development of new and innovative drugs.
Used in Agrochemical Industry:
(1E)-1-tert-Butoxy-1-(trimethylsilyloxy)propene is also utilized in the agrochemical industry as a precursor for the synthesis of agrochemicals. Its reactivity in organic synthesis reactions contributes to the creation of effective and targeted agrochemical products.
Used in Advanced Materials:
(1E)-1-tert-Butoxy-1-(trimethylsilyloxy)propene is used in the development of advanced materials due to its versatility in organic synthesis. The ability to form various organic compounds allows for the creation of materials with specific properties for specialized applications.
Used for Protection of Alcohol Functionality:
In chemical synthesis processes, (1E)-1-tert-Butoxy-1-(trimethylsilyloxy)propene is used to protect the alcohol functionality from undesired side reactions. The trimethylsilyl group in the molecule provides this protective feature, ensuring that the desired product is obtained without unwanted byproducts.
Check Digit Verification of cas no
The CAS Registry Mumber 72658-10-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,6,5 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 72658-10:
(7*7)+(6*2)+(5*6)+(4*5)+(3*8)+(2*1)+(1*0)=137
137 % 10 = 7
So 72658-10-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H22O2Si/c1-8-9(11-10(2,3)4)12-13(5,6)7/h8H,1-7H3/b9-8+
72658-10-7Relevant articles and documents
Synthesis of α-Heteroaryl Propionic Esters by Palladium-Catalyzed α-Heteroarylation of Silyl Ketene Acetals
Li, Bowen,Luo, Bangke,Blakemore, Caroline A.,Smith, Aaron C.,Widlicka, Daniel W.,Berritt, Simon,Tang, Wenjun
, p. 6439 - 6443 (2021)
A practical and efficient synthesis of α-heteroaryl propionic esters is developed by employing palladium-catalyzed α-heteroarylation of silyl ketene acetals, forming a wide variety of α-heteroaryl propionic esters with various substituents and functionalities in high yields. The success of this transformation is credited to the development of the bulky P,P═O ligand. The method has provided an efficient synthesis of α-heteroaryl propionic acids.
CHIRAL PHOSPHINES FOR PALLADIUM-CATALYZED ASYMMETRIC ALPHA-ARYLATION OF ESTER ENOLATES TO PRODUCE TERTIARY STEREOCENTERS IN HIGH ENANTIOSELECTIVITY
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Paragraph 00181-00182, (2013/03/26)
The disclosure provides new and improved methods for the Pd-catalyzed asymmetric α-arylation of ester compounds, which produce the corresponding α-aryl moiety in high enantioselectivity (generally >90% ee). The present methods utilize a palladium catalyst supported by new (R)-H8-BINOL-derived monophosphine ligands. The method is applicable to a wide variety of aryl triflate substrates having variations in both electronic and steric properties. These aryl triflate substrates react with various α-alkyl (Z)- and/or (E)-0-trimethylsilyl ketene acetals in the presence of a Pd catalyst, (R)-H8-BINOL-derived monophosphine ligand, and a mild activator, for example, LiOAC, to provide the asymmetric α-arylation of ester compounds in high ee.
Practical and robust method for regio- and stereoselective preparation of (E)-ketene tert-butyl TMS acetals and β-ketoester-derived tert-butyl (1Z,3E)-1,3-bis(TMS)dienol ethers
Okabayashi, Tomohito,Iida, Akira,Takai, Kenta,Nawate, Yuuya,Misaki, Tomonori,Tanabe, Yoo
, p. 8142 - 8145 (2008/02/12)
(Chemical Equation Presented) We developed an efficient, practical, robust method for the regio- and stereoselective preparation of (E)-ketene trimethylsilyl acetals (KSAs) derived from tert-butyl esters 1. The reaction was performed under convenient reac