72957-37-0 Usage
Description
GLY-HIS-LYS ACETATE SALT, also known as Gly-His-Lys, is a tripeptide composed of three amino acids: glycine, histidine, and lysine. It is present in human blood plasma at approximately 200ng/ml in association with α-globulin and albumin. The chemical properties of GLY-HIS-LYS ACETATE SALT include its appearance as a white powder.
Uses
Used in Pharmaceutical Industry:
GLY-HIS-LYS ACETATE SALT is used as a model peptide for N,N-dimethyl-N-methacryloxyethyl-N-(3-sulfopropyl)ammonium betaine based capillary electrophoresis separation studies. This application is crucial for the development and optimization of pharmaceutical techniques and methods.
Used in Biomedical Research:
GLY-HIS-LYS ACETATE SALT is used individually or as a complex with copper to test its effect on cytokines production in human normal fibroblasts cell lines. This application aids in understanding the role of this tripeptide in cellular processes and its potential therapeutic applications.
Used in Cell Culture:
GLY-HIS-LYS ACETATE SALT is used as a component of Coon's modified Ham's F-12 medium for culturing the Fischer rat thyroid follicular cell line, FRTL-5. This application is essential for maintaining the growth and function of specific cell types in laboratory settings, which can be crucial for various research and therapeutic purposes.
Used in Growth Factor Studies:
GLY-HIS-LYS ACETATE SALT is used in the study of Liver Cell Growth Factor, which is important for understanding the role of this tripeptide in liver cell growth and regeneration. This application can contribute to the development of treatments for liver diseases and conditions related to liver cell growth.
Biochem/physiol Actions
Gly-His-Lys (GHK) acetate salt displays affinity towards copper(II) ions. This property enables GHK to modulate the copper intake into cells. GHK is also involved in quenching toxic by-products generated by lipid peroxidation.
Check Digit Verification of cas no
The CAS Registry Mumber 72957-37-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,9,5 and 7 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 72957-37:
(7*7)+(6*2)+(5*9)+(4*5)+(3*7)+(2*3)+(1*7)=160
160 % 10 = 0
So 72957-37-0 is a valid CAS Registry Number.
InChI:InChI=1/C14H24N6O4.C2H4O2/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;1-2(3)4/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);1H3,(H,3,4)
