73021-84-8

Basic information

• Product Name: Methanesulfonamide, N-(4-oxo-2,5-cyclohexadien-1-ylidene)-
• CAS NO: 73021-84-8
• Molecular Formula: C7H7NO3S
• Molecular Weight: 185.203
• Mol File: 73021-84-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Methanesulfonamide, N-(4-oxo-2,5-cyclohexadien-1-ylidene)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonamide, N-(4-oxo-2,5-cyclohexadien-1-ylidene)-(73021-84-8)
• EPA Substance Registry System: Methanesulfonamide, N-(4-oxo-2,5-cyclohexadien-1-ylidene)-(73021-84-8)

Safety Data

• Hazardous Substances Data: 73021-84-8(Hazardous Substances Data)

Upstream product

• 51-78-5 p-aminophenol hydrochloride 
• 123-30-8 4-amino-phenol 
• 51767-39-6 4-(methylsulfonylamino)phenol 

Downstream Products

• 919966-54-4 N-(3-((1H-1,2,4-triazol-5-yl)thio)-4-hydroxyphenyl)methanesulfonamide 
• 1375149-24-8 C₃₁H₄₆N₂O₆S 
• 1375149-23-7 C₃₁H₄₆N₂O₆S 
• 141625-93-6 dronedarone hydrochloride 
• 51767-39-6 4-(methylsulfonylamino)phenol 
• 1278585-70-8 N-[2-butyl-3-(4-hydroxybenzoyl)-1-benzofuran-5-yl]methanesulfonamide 
• 1397749-85-7 phenyl 2-butyl-5-(methanesulfonamido)benzofuran-3-carboxylate 
• 1329684-17-4 methyl-2-[2-hydroxy-5-(methanesulfonamido)phenyl]-3-oxoheptanoate 
• 141625-93-6 2-(n-butyl)-3-(4-{3-[di(n-butyl)amino]propoxy}benzoyl)-5-(methanesulfonamido)benzofuran hydrochloride 
• 141626-36-0 dronedarone 
• 1369434-08-1 N-(4-hydroxy-3-tosylphenyl)methanesulfonamide 
• 1369434-07-0 N-[4-hydroxy-3-(4-methoxyphenylsulfonyl)phenyl]methanesulfonamide 
• 1369434-11-6 N-[4-hydroxy-3-(4-fluorophenylsulfonyl)phenyl]methanesulfonamide 
• 1369434-12-7 N-[4-hydroxy-3-(trifluoromethylsulfonyl)phenyl]methanesulfonamide 

Relevant articles and documents

PROCESS FOR SYNTHESIZING KETO-BENZOFURAN DERIVATIVES

The invention relates to a process for synthesizing benzofuran derivatives, in particular dronedarone of formula (D), comprising a step of Friedel-Crafts acylation starting from a sulfonamido-benzofuran ester intermediate.

KETOBENZOFURAN DERIVATIVES, METHOD FOR SYNTHESIZING SAME, AND INTERMEDIATES

The present disclosure relates to ketobenzofuran derivatives of the general formula (I): as well as to a method of synthesizing the same by coupling a quinonimine and an enaminone by a Nenitzescu reaction and to the intermediates of the synthesis thereof.

PROCESS FOR THE PREPARATION OF 3-AROYL-5-AMINOBENZOFURAN DERIVATIVES

The present invention relates to a process for the preparation of 3-aroyl -5- aminobenzofuran derivatives useful as antiarrhythmic drugs which avoids the use of nitro intermediates.