73031-42-2Relevant articles and documents
Improved Titanium Tetrachloride Procedure for Enamine Synthesis.II.Scope of the Reaction
Carlson, Rolf,Nilsson, Asa
, p. 49 - 54 (2007/10/02)
The scope of enamine formation by a procedure where the carbonyl compound is added to a preformed titanium tetrachloride-amine complex was investigated with a series of different types of carbonyl compounds and two secondary amines (morpholine and pyrrolidine).The carbonyl compounds include aldehydes, cyclic ketones and some substituted aryl alkyl ketones.Yields of isolated products were in the range 67-100 percent with the exception of the pyrrolidine enamine from camphor which gave 53 percent of the isolated product.