73101-79-8

Basic information

• Product Name: 5-ethoxy-6-methylpyridin-2-amine
• Synonyms: 5-ethoxy-6-methylpyridin-2-amine;6-Amino-3-ethoxy-6-methylpyridine;2-Amino-5-ethoxy-6-methylpyridine
• CAS NO: 73101-79-8
• Molecular Formula: C8H12N2O
• Molecular Weight: 152.19368
• Mol File: 73101-79-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 261.3 °C at 760 mmHg
• Flash Point: 111.8 °C
• Appearance: /
• Density: 1.073 g/cm³
• Vapor Pressure: 0.0117mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 5-ethoxy-6-methylpyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ethoxy-6-methylpyridin-2-amine(73101-79-8)
• EPA Substance Registry System: 5-ethoxy-6-methylpyridin-2-amine(73101-79-8)

Safety Data

• Hazardous Substances Data: 73101-79-8(Hazardous Substances Data)

Usage

General Description

5-ethoxy-6-methylpyridin-2-amine is a chemical compound with the molecular formula C8H12N2O. It belongs to the class of amines and is characterized by the presence of an ethoxy and a methyl group on the pyridine ring. 5-ethoxy-6-methylpyridin-2-amine is commonly used in the field of chemistry and pharmaceuticals for its various applications. It can be utilized in the synthesis of organic compounds and pharmaceutical drugs, as well as in research and development of new materials. Additionally, it has potential use in the field of agrochemicals and pesticides due to its chemical properties. However, it is important to handle this chemical with care and in accordance with safety guidelines, as it may have potential hazards associated with its handling and use.

InChI:InChI=1/C8H12N2O/c1-3-11-7-4-5-8(9)10-6(7)2/h4-5H,3H2,1-2H3,(H2,9,10)

Upstream product

• 73101-78-7 3-ethoxy-6-nitro-2-picoline 
• 6652-01-3 3-ethoxy-2-methyl-pyridine 

Downstream Products

• 73101-90-3 5-ethyl-8-oxo-2,3,5,8-tetrahydrofuro<3,2-b><1,8>naphthyridine-7-carboxylic acid 
• 73101-87-8 5-ethyl-8-oxo-5,8-dihydrofuro<3,2-b><1,8>naphthyridine-7-carboxylic acid 
• 83593-35-5 ethyl 6-benzyloxy-1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-7-carboxylate 
• 77016-54-7 3-(6-ethoxy-3-ethoxycarbonyl-4-hydroxy-1,8-naphthyridin-7-yl)acrylic acid 
• 79905-33-2 ethyl 6-benzyloxy-7-(2-dimethylaminovinyl)-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate 
• 79905-34-3 6-benzyloxy-7-(2,2-diethoxyethyl)-1-ethyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid 

Relevant articles and documents

Condensed 4-aminopyridines with antirheumatic activity

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which one of A or B represents N and the other represents N or C--R3 ; R1 represents hydrogen, halo, alkyl, hydroxy, carboxyalkenyl, alkoxycarbonylalkenyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxy, halogenated alkyl, carboxy, alkoxycarbonyl, alkanoylamino or carbamoylalkenyl; R2 represents hydrogen, alkyl, halo, alkoxy, hydroxy, alkanoyloxy, or phenoxy; R3 represents hydrogen or alkyl; R4 represents hydrogen, halo, alkoxycarbonyl, cyano, benzyloxycarbonyl, alkanoyl, benzoyl, alkyl, carboxy, alkylthio or carbamoyl; R5 represents hydrogen or alkyl; R9 represents hydrogen or alkyl; R10 represents phenyl, pyridyl or pyrimidinyl substituted by OR6 and optionally further substituted wherein R6 represents hydrogen, alkyl, alkoxycarbonyl or carbamoyl, alicyclic hydrocarbon, phenyl, cycloalkylalkyl, arylalkyl or pyridyl; or when R10 represents phenyl, OR6 represents a monosaccharide group or a disaccharide group; which are antirheumatic agents. Compositions containing these compounds and processes to prepare them are also disclosed.

Synthesis of antimicrobial agents. VI. Studies on the synthesis of furo[3,2-b][1,8]naphthyridine derivatives

As a part of our search for new antibacterial agents, 5-ethyl-8-oxo-5,8-dihydrofuro[3,2-b][1,8]naphthyridine-7-carboxylic acid and its 2,3-dihydrofuro derivative, the 4-aza analogue of droxacin, were synthesized and their antibacterial activities were tested. Both compounds exhibited high antibacterial activities and a broad antibacterial spectrum. In an attempt to find a suitable method for industrial-scale synthesis of these compounds, several methods for the furan ring cyclization of 6,7-disubstituted 1,8-naphthyridine-3-carboxylate derivatives were compared.