73389-49-8Relevant articles and documents
Inhibitors of sterol synthesis. Synthesis and spectral properties of 3β-hydroxy-5α-cholestan-15-one and its 14β-epimer and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
Siddiqui,Wilson,Parish,Gerst,Pinkerton,Schroepfer Jr.
, p. 1 - 15 (2007/10/02)
3β-Hydroxy-5α-cholestan-15-one (2a) and its 14β-epimer 2b were prepared from 3β-acetoxy-5α-cholest-8(14)-ene (3). Hydroboration of 3 at 45-50°C gave a mixture of 5α,14α-cholestane-3β,15α-diol and 5α,14β-cholestane-3β,15β-diol, which were separated on sili