73397-12-3Relevant articles and documents
Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity
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, (2008/06/13)
The present invention relates to novel enzymatic substrates with the following general formula: where R1, R2, R3, R4, R5, R6, A and X are as defined in claim 1, the reaction media comprising the same and the use thereof for the detection and/or identification and/or quantification of microorganisms expressing at least one peptidase activity.
Quinone Chemistry. Reaction of 2,3-Dichloro-1,4-naphthoquinone with 2-Aminophenols in Pyridine
Agarwal, Nand L.,Schaefer, Wolfram
, p. 5144 - 5149 (2007/10/02)
The reaction of 2,3-dichloro-1,4-naphthoquinone (1) and 2-aminophenols (2) in pyridine furnished substituted 6-chloro-5H-benzophenoxazin-5-one (10), 5H-benzophenoxazin-5-one (8), 5H-benzophenoxazin-5-one-6-pyridinium chloride (6), 2-(2-hydroxyanilino)-1,4-naphthoquinone-3-pyridinium chloride (5), and 12H-benzophenoxazine-6,11-dione (7).It was observed that the nature and yields of the reaction products were greatly influenced by the substituent present in 2.The reaction mechanism for the formation of all products is discussed, and spectroscopic data are also given.This reaction for the first time led to a development of a novel, convenient synthesis of a new class of heterocyclic quinones (7).