73441-43-7

Basic information

• Product Name: Benzenemethanamine, alpha-methyl-4-(1-methylethyl)- (9CI)
• Synonyms: Benzenemethanamine, alpha-methyl-4-(1-methylethyl)- (9CI);1-(4-isopropylphenyl)ethanamine(SALTDATA: FREE);1-(4-propan-2-ylphenyl)ethanamine
• CAS NO: 73441-43-7
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.25938
• Product Categories: ISOPROPYL
• Mol File: 73441-43-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 236.1°C at 760 mmHg
• Flash Point: 101.5°C
• Appearance: /
• Density: 0.923g/cm³
• Vapor Pressure: 0.0483mmHg at 25°C
• Refractive Index: 1.517
• PKA: 9.18±0.10(Predicted)
• CAS DataBase Reference: Benzenemethanamine, alpha-methyl-4-(1-methylethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, alpha-methyl-4-(1-methylethyl)- (9CI)(73441-43-7)
• EPA Substance Registry System: Benzenemethanamine, alpha-methyl-4-(1-methylethyl)- (9CI)(73441-43-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 73441-43-7(Hazardous Substances Data)

Usage

Description

Benzenemethanamine, alpha-methyl-4-(1-methylethyl)(9CI), also known as alpha-methyl-4-isopropylbenzylamine, is a chemical compound belonging to the phenethylamine class. It has the molecular formula C11H17N and is characterized as a colorless liquid with a strong odor. Benzenemethanamine, alpha-methyl-4-(1-methylethyl)(9CI) is considered hazardous due to its potential to cause skin and eye irritation and is also flammable, necessitating careful handling in laboratory or industrial settings.

Uses

Used in Pharmaceutical Industry:
Benzenemethanamine, alpha-methyl-4-(1-methylethyl)(9CI) is utilized as a precursor in the synthesis of various drugs, playing a crucial role in the development of medicinal compounds.
Used in Organic Chemistry Experiments:
Benzenemethanamine, alpha-methyl-4-(1-methylethyl)(9CI) also serves as a reagent in organic chemistry, aiding in various experimental procedures and reactions.

InChI:InChI=1/C11H17N/c1-8(2)10-4-6-11(7-5-10)9(3)12/h4-9H,12H2,1-3H3

Upstream product

• 5359-04-6 1-(4-(prop-1-en-2-yl)phenyl)ethan-1-one 
• 645-13-6 4-isopropylacetophenone 
• 98571-16-5 1-(4-Isopropyl-phenyl)-ethylamine; compound with (E)-3-phenyl-acrylic acid 
• 98405-01-7 1-(4-Isopropylphenyl)-ethylamine*mandelic acid salt 
• 98571-16-5 1-(4-Isopropyl-phenyl)-ethylamine; compound with (E)-3-phenyl-acrylic acid 
• 98405-01-7 1-(4-Isopropylphenyl)-ethylamine*mandelic acid 

Downstream Products

• 98571-19-8 (S)-1-(4-Isopropyl-phenyl)-ethylamine; compound with 2-hydroxy-succinic acid 
• 98571-16-5 1-(4-Isopropyl-phenyl)-ethylamine; compound with (E)-3-phenyl-acrylic acid 
• 98571-16-5 1-(4-Isopropyl-phenyl)-ethylamine; compound with (E)-3-phenyl-acrylic acid 
• 98405-01-7 1-(4-Isopropylphenyl)-ethylamine*mandelic acid 
• 98405-01-7 1-(4-Isopropylphenyl)-ethylamine*mandelic acid salt 
• 73441-45-9 N,N-dimethyl-1-(4-isopropylphenyl)-ethylamine 

Relevant articles and documents

Catalytic asymmetric oxidative carbonylation-induced kinetic resolution of sterically hindered benzylamines to chiral isoindolinones

A highly enantioselective kinetic resolution of sterically hindered benzylamines has been achieved for the first time through transition-metal-catalyzed oxidative carbonylation, in which the new KR strategy offered a new approach to afford chiral isoindolinones (er up to 97?:?3) and the origin of chemoselectivity and stereoselectivity was confirmed by density functional theory (DFT) calculations.

Synthesis and Optical Resolution of 1-(4-Isopropylphenyl)-ethylamine

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