73718-09-9

Basic information

• Product Name: 3-[4-(DIMETHYLAMINO)PHENYL]PROPANOIC ACID
• Synonyms: CHEMBRDG-BB 4013887;AKOS BB-9212;3-[4-(DIMETHYLAMINO)PHENYL]PROPANOIC ACID;3-(4-DIMETHYLAMINO-PHENYL)-PROPIONIC ACID;3-[4-(dimethylamino)phenyl]propanoic acid hydrochloride;benzenepropanoic acid, 4-(dimethylamino)-;3-[4-(dimethylamino)phenyl]propanoic acid(SALTDATA: HCl);4-(Dimethylamino)benzenepropanoic acid
• CAS NO: 73718-09-9
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.24
• Mol File: 73718-09-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 184-185 °C
• Boiling Point: 341.6 °C at 760 mmHg
• Flash Point: 160.4 °C
• Appearance: /
• Density: 1.127 g/cm³
• Vapor Pressure: 3.06E-05mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.53±0.10(Predicted)
• CAS DataBase Reference: 3-[4-(DIMETHYLAMINO)PHENYL]PROPANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-(DIMETHYLAMINO)PHENYL]PROPANOIC ACID(73718-09-9)
• EPA Substance Registry System: 3-[4-(DIMETHYLAMINO)PHENYL]PROPANOIC ACID(73718-09-9)

Safety Data

• Hazardous Substances Data: 73718-09-9(Hazardous Substances Data)

Usage

General Description

3-[4-(Dimethylamino)phenyl]propanoic acid, also known as Rhodanine-3-acetic acid, is a chemical compound that has been extensively studied for its broad range of potential applications in various fields. Its chemical formula is C11H15NO2, and it has a molar mass of 193.24 g/mol. This organic molecule contains both amine and carboxylic acid functional groups, making it a versatile reactant in many different chemical reactions. Its unique structure gives it various properties, such as the ability to form salts and engage in hydrogen bonding. It has potential uses in dye manufacturing and as a corrosion inhibitor due to its interactions with metals. However, its human health effects and toxicological properties are currently not fully understood, necessitating further research and caution in handling.

InChI:InChI=1/C11H15NO2/c1-12(2)10-6-3-9(4-7-10)5-8-11(13)14/h3-4,6-7H,5,8H2,1-2H3,(H,13,14)/p-1

Upstream product

• 1552-96-1 p-dimethylaminocinnamic acid 
• 1552-97-2 3-[4-(dimethylamino)phenyl]-2-propenoic acid ethyl ester 
• 3984-22-3 2-vinyl-1,3-dioxolane 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 50438-75-0 2-(4-dimethylaminophenyl)ethyl alcohol 
• 139670-57-8 2-(4-dimethylaminophenyl)ethyl tosylate 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 75567-86-1 3-(4-dimethylaminophenyl)propionic acid methyl ester 
• 15795-57-0 5-(4-N,N-dimethylaminobenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione 

Downstream Products

• 52632-05-0 4-Dimethylaminophenethylamine 
• 75567-86-1 3-(4-dimethylaminophenyl)propionic acid methyl ester 
• 139670-47-6 (1R,2R)-trans-cyclohexanediol mono-p-dimethylaminohydrocinnamate 
• 139670-46-5 (1R,2R)-trans-cyclohexanediol bis-p-dimethylaminohydrocinnamate 
• 1613696-27-7 4-(2-{5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[2-(morpholin-4-yl)ethyl]-1H-benzimidazol-2-yl}ethyl)-N,N-dimethylaniline 

Relevant articles and documents

Direct synthesis of 3-arylpropionic acids by tetraphosphine/palladium catalysed Heck reactions of aryl halides with acrolein ethylene acetal

Through the use of [PdCl(C3H5)]2/Cis,cis, cis-1,2,3,4-tetrakis(diphenylphosphinomethyl)cyclopentane as a catalyst, a range of aryl bromides undergoes Heck reaction with acrolein ethylene acetal. With this acetal, the selective formation of 3-arylpropionic acids/esters was observed. The functional group tolerance on the aryl halide is remarkable; substituents such as fluoro, methyl, methoxy, acetyl, formyl, benzoyl, nitro or nitrile are tolerated. Furthermore, this catalyst can be used at low loading, even for reactions of sterically hindered aryl bromides. Graphical Abstract.

Process for the preparation of carboxylic acids and derivatives of them

The subject matter of the invention is a process for the preparation of carboxylic acids and derivatives of them of the general formula STR1 wherein R means hydrogen, or a C1-4 alkyl or a (C1-5 alkoxy)carbonyl group, R1 is as defined in claim 1, R7 stands for hydrogen or a C1-7 alkyl group and R8 means hydrogen or a carboxyl group, by reacting a 1,3-dioxane-4,6-dione derivative of the general formula STR2 wherein R9 stands for a C1-4 alkyl group or a phenyl group, optionally monosubstituted by halogen and R10 stands for hydrogen or a C1-5 alkyl group or R9 and R10 together form a pentamethylene group, and an aldehyde or ketone of the general formula STR3 in the presence of formic acid.

LONG-RANGE EXCITON COUPLING FROM DIPYRRINONE CHROMOPHORES

Dipyrrinone chromophores, attached by their acid termini to give (1R,2R)-cyclohexanediol dipropionate and diacetate esters (xanthobilirubinate and nor-xanthobilirubinate, respectively), interact through exciton coupling, as evidenced by intense bisignate