73771-04-7 Usage
Description
[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate is a complex organic compound with a unique molecular structure. It is a derivative of a cyclopenta[a]phenanthren compound, featuring a propanoate group and an ethoxycarbonyloxy group. [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate has a wide range of potential applications due to its chemical properties and structure.
Uses
Used in Pharmaceutical Industry:
[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate is used as a pharmaceutical agent for its anti-inflammatory properties. It is particularly effective in treating cutaneous inflammatory disorders such as eczema and psoriasis due to its potent topical anti-inflammatory activity and minimal systemic effects.
Used in Topical Corticosteroid Formulations:
In the field of dermatology, [2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate is used as a glucocorticoid in topical formulations. It exhibits anti-inflammatory activity comparable to other corticosteroids when administered topically, making it a valuable component in treatments for various skin conditions.
Used in Wound Healing Applications:
[2-(17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] propanoate is also utilized in wound healing processes. Topical administration of this compound has been shown to induce wound healing in hairless mice, suggesting its potential use in accelerating the healing of various skin injuries and conditions.
Indications
Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.
Check Digit Verification of cas no
The CAS Registry Mumber 73771-04-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,7,7 and 1 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 73771-04:
(7*7)+(6*3)+(5*7)+(4*7)+(3*1)+(2*0)+(1*4)=137
137 % 10 = 7
So 73771-04-7 is a valid CAS Registry Number.
InChI:InChI=1/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1
73771-04-7Relevant articles and documents
Method for preparing prednicarbate intermediate
-
Paragraph 0043-0045, (2020/02/07)
The invention relates to a method for preparing a prednicarbate key intermediate (a compound of a formula III shown in the description). According to the method, a compound of a formula II shown in the description is adopted as a raw material, water and ethanol are adopted as solvents, and the compound of the formula III shown in the description is prepared through a hydrolysis reaction under theacid condition. Compared with the prior art, the conversion rate of the compound of the formula II shown in the description is increased, problems that the compound of the formula III shown in the description is not easy to separate, purify, crystallize and the like can be solved, the compound of the formula III with high purity can be conveniently and rapidly prepared, and the method is applicable to industrial production.
Composition for the topical treatment of poison ivy and other forms of contact dermatitis
-
, (2008/06/13)
Composition for topical administration comprising (a) a corticosteroid, and (b) a drying agent.