73771-35-4

Basic information

• Product Name: 3-(METHYLTHIO)BENZALDEHYDE
• Synonyms: 3-(METHYLTHIO)BENZALDEHYDE;3-(methylthio)benzaldehyde(SALTDATA: FREE);3-Methylsulfanylbenzaldehyde
• CAS NO: 73771-35-4
• Molecular Formula: C₈H₈OS
• Molecular Weight: 152.21
• Mol File: 73771-35-4.mol
• Article Data: 25

Chemical Properties

• Boiling Point: 254.099°C at 760 mmHg
• Flash Point: 122.18°C
• Appearance: /
• Density: 1.138g/cm³
• Vapor Pressure: 0.018mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: 3-(METHYLTHIO)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(METHYLTHIO)BENZALDEHYDE(73771-35-4)
• EPA Substance Registry System: 3-(METHYLTHIO)BENZALDEHYDE(73771-35-4)

Safety Data

• Hazardous Substances Data: 73771-35-4(Hazardous Substances Data)

Usage

General Description

3-(Methylthio)benzaldehyde is an organic compound with the chemical formula C8H8OS. It is a clear, colorless to pale yellow liquid with a strong odor. This chemical is commonly used as a flavoring agent in the food industry, particularly in the production of raspberry, blackberry, and other fruit flavors. It is also used in the synthesis of pharmaceuticals and as a fragrance ingredient in perfumes and cosmetics. Additionally, 3-(methylthio)benzaldehyde has been studied for its potential antimicrobial and antifungal properties, making it a versatile compound with a range of applications.

InChI:InChI=1/C8H8OS/c1-10-8-4-2-3-7(5-8)6-9/h2-6H,1H3

Upstream product

• 59083-33-9 (3-methylsulfanyl-phenyl)-methanol 
• 33733-73-2 3-bromo-1-(methylthio)benzene 
• 122-51-0 orthoformic acid triethyl ester 
• 201851-07-2 2-(3-(methylthio)phenyl)-1,3-dioxolane 
• 4869-59-4 3-mercapto benzoic acid 
• 74-88-4 methyl iodide 
• 17789-14-9 3-(1,3-dioxolan-2-yl)-phenylbromide 
• 75148-49-1 3-bromobenzaldehyde diethylacetal 
• 6320-01-0 3-Bromothiophenol 
• 825-99-0 3-methylsulfanyl-benzoic acid 
• 616196-32-8 N-methoxy-N-methyl-3-(methylsulfanyl)benzamide 
• 130416-73-8 3-iodothioanisole 
• 68-12-2 N,N-dimethyl-formamide 
• 1783-81-9 3-methylmercaptoaniline 

Downstream Products

• 882-15-5 2-Nitro-1-(3-methylmercapto-phenyl)-propen-⁽¹⁾ 
• 129747-73-5 3-thiophenecarboxaldehyde 
• 110841-66-2 N-(3-methylthiobenzyl)allylamine 
• 90265-74-0 N-(3-methylthiobenzyl)aminoacetaldehyde dimethyl acetal 
• 106291-39-8 N-benzyl-3-methylthiobenzylamine 
• 90265-77-3 N-(3-methylthiobenzyl)-1-phenyl-2-aminoethanol 
• 825-99-0 3-methylsulfanyl-benzoic acid 
• 165806-89-3 N-[3-methylthiophenyl-(tolylthio)methyl]formamide 
• 368447-70-5 3-(methylsulfanyl)benzaldehyde (E)-O-[(1S)-2-hydroxy-1-phenylethyl]oxime 
• 284047-77-4 3-(methylthio)mandelic acid 
• 602301-51-9 (S)-Acetoxy-(3-methylsulfanyl-phenyl)-acetic acid 

Relevant articles and documents

SUBSTITUTED BENZIMIDAZOLES AS POTASSIUM CHANNEL INHIBITORS

The present invention relates to a compound of the general formula (I). The compounds of formula I are useful for treatment of a cardiac disease, disorder or condition in a mammal.

Molecular Engineering of UV/Vis Light-Emitting Diode (LED)-Sensitive Donor–π–Acceptor-Type Sulfonium Salt Photoacid Generators: Design, Synthesis, and Study of Photochemical and Photophysical Properties

A series of donor–π–acceptor-type sulfonium salt photoacid generators (PAGs) were designed and synthesized by systematically changing electron-donating groups, π-conjugated systems, electron-withdrawing groups, and the number of branches through molecular engineering. These PAGs can effectively decompose under UV/Vis irradiation from a light-emitting diode (LED) light source because of the matching absorption and emitting spectra of the LEDs. The absorption and acid-generation properties of these sulfonium salts were elucidated by UV/Vis spectroscopy and so forth. Results indicated that the PAG performance benefited from the introduction of strong electron-donating groups, specific π-conjugated structures, certain electron-withdrawing groups, or two-branched structures. Most sulfonium salts showed potential as photoinitiators under irradiation by a wide variety of UV and visible LEDs.

Synthesis and SAR study of new thiazole derivatives as vascular adhesion protein-1 (VAP-1) inhibitors for the treatment of diabetic macular edema: Part 2

Novel thiazole derivatives were synthesized and evaluated as vascular adhesion protein-1 (VAP-1) inhibitors. Although our previous compound 1 showed potent VAP-1 inhibitory activity, the activity differed between humans and rats. This issue was overcome by a hybrid design using human VAP-1 specific inhibitor 2, which was found by high-throughput screening (HTS), a docking study of a human VAP-1 homology model, and an analysis of sequence information for humans and rats. As a result, we identified compound 35c, which showed strong VAP-1 inhibitory activity (human IC50 of 20 nM; rat IC50 of 72 nM) and significant inhibitory effects in the ex vivo test.