7379-51-3

Basic information

• Product Name: 4-(Methylthio)-3,5-xylenol
• Synonyms: 4-(Methylthio)-3,5-xylenol;3,5-Dimethyl-4-(methylthio)phenol;4-Methylthio-3,5-dimethylphenol;3,5-Dimethyl-(4-thiomethyl)Phenol;Brn 2045340;Einecs 230-947-7;Phenol, 3,5-dimethyl-4-(methylthio)-
• CAS NO: 7379-51-3
• Molecular Formula: C₉H₁₂OS
• Molecular Weight: 168.26
• EINECS: 230-947-7
• Mol File: 7379-51-3.mol
• Article Data: 1

Chemical Properties

• Melting Point: 64-65.5 °C
• Boiling Point: 267.9 °C at 760 mmHg
• Flash Point: 130.8 °C
• Appearance: /
• Density: 1.12 g/cm³
• Vapor Pressure: 0.0048mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
• PKA: 10.03±0.23(Predicted)
• CAS DataBase Reference: 4-(Methylthio)-3,5-xylenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Methylthio)-3,5-xylenol(7379-51-3)
• EPA Substance Registry System: 4-(Methylthio)-3,5-xylenol(7379-51-3)

Safety Data

• Hazardous Substances Data: 7379-51-3(Hazardous Substances Data)

Usage

Description

4-(Methylthio)-3,5-xylenol, also known as 3,5-Dimethyl-4-(methylthio)phenol, is an organic compound with the chemical formula C10H14OS. It is a colorless to pale yellow liquid with a strong, musty odor. 4-(Methylthio)-3,5-xylenol is characterized by the presence of a methylthio group (-SH) attached to a xylenol moiety, which consists of a methylated phenol with two methyl groups in the 3 and 5 positions.

Uses

Used in Pesticide Industry:
4-(Methylthio)-3,5-xylenol is used as an insecticide for controlling various pests in agricultural settings. It is effective against a wide range of insects, including aphids, mites, and caterpillars, due to its ability to disrupt their nervous systems and cause paralysis and death.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-(Methylthio)-3,5-xylenol is utilized as an intermediate in the synthesis of methiocarb, a widely used insecticide and acaricide. Methiocarb is known for its broad-spectrum activity against various pests and is used in both agricultural and residential applications to protect crops and control household pests.
Used in Chemical Synthesis:
4-(Methylthio)-3,5-xylenol can also be used as a building block in the synthesis of other organic compounds, such as pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure and functional groups make it a versatile starting material for the development of new molecules with potential applications in various industries.

InChI:InChI=1/C9H12OS/c1-6-4-8(10)5-7(2)9(6)11-3/h4-5,10H,1-3H3

Upstream product

• 624-92-0 Dimethyldisulphide 
• 108-68-9 3,5-Dimethylphenol 

Downstream Products

• 60309-88-8 Propyl-carbamic acid 3,5-dimethyl-4-methylsulfanyl-phenyl ester 
• 64406-59-3 Methoxymethyl-carbamic acid 3,5-dimethyl-4-methylsulfanyl-phenyl ester 
• 132529-75-0 4-(3,5-dimethyl-4-methylthiophenoxy)benzonitrile 
• 64381-03-9 2-(2,4,5-Trichloro-phenoxy)-propionic acid (3,5-dimethyl-4-methylsulfanyl-phenoxycarbonylamino)-methyl ester 
• 64381-34-6 4-(2,4-Dichloro-phenoxy)-butyric acid (3,5-dimethyl-4-methylsulfanyl-phenoxycarbonylamino)-methyl ester 
• 42571-82-4 1-[4-(methylthio)-3,5-xylyl] chloroformate 
• 68721-65-3 Dimethyl-carbamic acid 3,5-dimethyl-4-methylsulfanyl-phenyl ester 
• 53325-82-9 3-[(Dichloro-fluoro-methylsulfanyl)-trifluoromethyl-amino]-benzoic acid 3,5-dimethyl-4-methylsulfanyl-phenyl ester 
• 53503-31-4 4-[(Dichloro-fluoro-methylsulfanyl)-trifluoromethyl-amino]-benzoic acid 3,5-dimethyl-4-methylsulfanyl-phenyl ester 

Relevant articles and documents

Process for the production of N-methylcarbamates

Process for the production of N-methylcarbamates: STR1 (wherein RO- is the radical of a substituted phenol or of a naphthol), wherein: in a first reaction step methylamine and diphenyl carbonate are reacted with each other, operating in the liquid phase and as a continuous process, in order to form phenol and phenyl-N-methylurethane; in a second reaction step phenyl-N-methylurethane, within the related reaction mixture outcoming from the first step, is thermally continuously decomposed, to yield a gaseous stream containing methyl isocyanate, from which the components different than methyl isocyanate are condensed off; in a third step the methyl isocyanate stream, outcoming from the second step, after an optional preliminary condensation, is continuously fed and contacted with a solution of a substituted phenol or of a naphthol in an inert organic solvent, containing a basic catalyst, to form N-methylcarbamate (I); N-methylcarbamate (I) is finally recovered from the reaction mixture outcoming from the third step.