73838-25-2

Basic information

• Product Name: Thiophene, 3-[[(4-methylphenyl)sulfonyl]methyl]-
• CAS NO: 73838-25-2
• Molecular Formula: C12H12O2S2
• Molecular Weight: 252.358
• Mol File: 73838-25-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Thiophene, 3-[[(4-methylphenyl)sulfonyl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiophene, 3-[[(4-methylphenyl)sulfonyl]methyl]-(73838-25-2)
• EPA Substance Registry System: Thiophene, 3-[[(4-methylphenyl)sulfonyl]methyl]-(73838-25-2)

Safety Data

• Hazardous Substances Data: 73838-25-2(Hazardous Substances Data)

Upstream product

• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 36331-50-7 thiophene-3-carboxaldehyde tosylhydrazone 
• 1950-78-3 p-toluenesulfonyl iodide 
• 34846-44-1 3-Bromomethylthiophene 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 98-59-9 p-toluenesulfonyl chloride 
• 2746-23-8 3-(chloromethyl)thiophene 

Downstream Products

• 82166-44-7 (4S,5aR,9aR)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene 
• 82112-44-5 (4R,5aR,9aR)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene 
• 82166-46-9 (4R,5aR,9aS)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene 
• 82166-48-1 (4S,5aR,9aS)-6,6,9a-Trimethyl-4-(toluene-4-sulfonyl)-4,5,5a,6,7,8,9,9a-octahydro-naphtho[1,2-b]thiophene 
• 186027-54-3 3-Cyclohexylidene-1-diazo-1-thiophen-3-yl-propan-2-one 
• 219702-93-9 1-Cyclohexylidene-3-thiophen-3-yl-propan-2-one 
• 221253-17-4 1-(cyclohex-2-enyl)-3-diazo-3-(3-thienyl)propan-2-one 
• 221253-09-4 1-(cyclohex-2-enyl)-3-(3-thienyl)propan-2-one 
• 221253-01-6 1-(cyclohex-2-enyl)-3-(3-thienyl)-3-(toluene-4-sulfonyl)propan-2-one 
• 219702-91-7 3-Cyclohexylidene-1-thiophen-3-yl-1-(toluene-4-sulfonyl)-propan-2-one 
• 82112-39-8 3-[(E)-4,8-Dimethyl-1-(toluene-4-sulfonyl)-nona-3,7-dienyl]-thiophene 
• 73838-26-3 1-(3-Thienyl)-1-(p-toluenesulfonyl)-4-methylpent-3-ene 

Relevant articles and documents

Visible-Light-Catalyzed in Situ Denitrogenative Sulfonylation of Sulfonylhydrazones

A photocatalyzed in situ denitrogenative sulfonylation of N-arylsulfonyl hydrazones has been developed. This transformation provides a low-carbon strategy to assemble arylalkyl sulfones in a stepwise denitrogenation/sulfonylation manner.

Homolytic Displacement at Saturated Carbon in Organocobalamines. Part 4

Benzyl and para-substituted benzylcobaloximes react with substituted arenesulphonyl chlorides under photochemical and anaerobic conditions at 0 deg C to give a variety of products including the sulphones, bibenzyls, and benzyl ethers of dimethylglyoxime in variable yields.However, when the reactions are carried out in the presence of a 1 mol excess of pyridine, the yield of sulphones is increased by at least 20percent in each case.The corresponding yield of bibenzyls is decreased and no trace of the benzyl ether of dimethylglyoxime is formed.On the other hand, the reaction of heteroaromatic methyl cobaloximes with arenesulphonyl chlorides form the corresponding sulphones as the exclusive organic product in good yield and with no side products.The reactions are interpreted in terms of a direct attack of the arenesulphonyl radical on the α carbon of the benzyl and heteroaromatic methyl ligand.

HOMOLYTIC DISPLACEMENT AT CARBON. X. TOLUENESULPHONYL IODIDE AS A SOURCE OF TOLUENESULPHONYL RADICALS FOR THE FORMATION OF ALLYL-, BENZYL-, CYCLOPROPYLCARBINYL-, SPIROCYCLOPROPYLCYCLOALKYL-, BICYCLOALKYL-, AND BICYCLOALKYL-4-TOLYLSULPHONES FROM ORGANOCOBALOXIMES

4-Toluenesulphonyl iodide reacts thermally at alkylsulphone.Spiro- and bicyclo-alkyl compounds are also formed with other free radical precursors.The reactions are believed to take place through a chain mechanism in which cobaloxime(II), present adventitiously or formed by partial homolysis of the substrate, abstracts iodine from the toluenesulphonyl iodide to give the toluenesulphonyl radical, which attacks the organic ligand of the cobaloxime, preferably at the terminal olefinic carbon, thereby displacing cobaloxime(II) and giving the observed organic product.