7391-62-0

Basic information

• Product Name: 5-butyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione
• CAS NO: 7391-62-0
• Molecular Formula: C₁₀H₁₆N₂O₃
• Molecular Weight: 212.2456
• Mol File: 7391-62-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 288.3°C at 760 mmHg
• Flash Point: 113.2°C
• Density: 1.125g/cm³
• Vapor Pressure: 0.00236mmHg at 25°C
• Refractive Index: 1.484
• CAS DataBase Reference: 5-butyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-butyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione(7391-62-0)
• EPA Substance Registry System: 5-butyl-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione(7391-62-0)

Safety Data

• Hazardous Substances Data: 7391-62-0(Hazardous Substances Data)

Upstream product

• 96-31-1 N,N'-Dimethylurea 
• 534-59-8 n-butylmalonic acid 
• 769-42-6 1,3-dimethylbarbituric acid 
• 102-82-9 tributyl-amine 

Relevant articles and documents

Mono C-alkylation and mono C-benzylation of barbituric acids through zinc/acid reduction of acyl, benzylidene, and alkylidene barbiturate intermediates

Through systematic exploration of reaction conditions, very efficient preparative procedures for obtaining large quantities of substituted 5-alkyl and 5-benzylbarbituric acids were developed. The procedure involves a two step preparation in which the second step is zinc dust/acid reduction. For preparation of 5-alkylbarbiturates, the first step is the preparation of either 5-acyl or 5-alkylidenebarbiturate. If 5-benzylbarbiturate is the target product, then the first step includes the preparation of 5-benzylidene. Regardless of the nature of the first step, all reactions presented synthetic yields around 90% and isolation and purification involves only crystallization.