741-76-4

Basic information

• Product Name: 2-(morpholin-4-yl)-3-phenylquinazolin-4(3H)-one
• Synonyms: 2-(morpholin-4-yl)-3-phenylquinazolin-4(3H)-one
• CAS NO: 741-76-4
• Molecular Weight: 307.352
• Mol File: 741-76-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(morpholin-4-yl)-3-phenylquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(morpholin-4-yl)-3-phenylquinazolin-4(3H)-one(741-76-4)
• EPA Substance Registry System: 2-(morpholin-4-yl)-3-phenylquinazolin-4(3H)-one(741-76-4)

Safety Data

• Hazardous Substances Data: 741-76-4(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 31162-13-7 2-azidobenzoic acid 
• 103-71-9 phenyl isocyanate 
• 1218906-34-3 N-(2-iodophenyl)-N'-phenyldicarbodiimide 
• 13939-06-5 molybdenum hexacarbonyl 
• 603-23-6 3-phenyl-2,4-(1H,3H)-quinazolinedione 
• 118-92-3 anthranilic acid 
• 32045-49-1 ethyl-o-aminobenzoate hydrochloride 
• 622403-42-3 1-phenyl-3-(2-ethoxycarbonylphenyl) carbodiimide 
• 727-62-8 2-chloro-3-phenylquinazoline-4-(3H)-one 

Relevant articles and documents

Molybdenum-mediated synthesis of quinazolin-4(3H)-ones via cyclocarbonylation using microwave irradiation

A new, efficient and practical synthesis of quinazolin-4(3H)-ones is reported via molybdenum-mediated cyclocarbonylation using microwave irradiation. These methods allow access to a wide range of quinazolin-4(3H)-ones in reasonable yields without the need for gaseous carbon monoxide and palladium catalysts. A range of reactions illustrating the wide scope of this chemistry was carried out and all proceeded in reasonable yields.

Solid-phase synthesis of 3H-Quinazolin-4-ones based on an aza Wittig-mediated annulation strategy

Aza Wittig-mediated annulation provides a highly efficient and straightforward strategy for the parallel synthesis of 3H-quinazolin-4-ones on solid support. The products were recovered in good yields and exhibited excellent purities.