74209-33-9 Usage
Description
1H-INDAZOLE,3-CHLORO-7-NITROis a chemical compound with the molecular formula C7H5ClN4O2. It is a nitro derivative of 1H-indazole, which is a heterocyclic aromatic organic compound. The presence of the chloro and nitro groups in this compound gives it potential use as a building block in the synthesis of other organic compounds, particularly in the pharmaceutical industry. Its structural features and reactivity make it valuable for the creation of new drugs or for other synthetic applications.
Used in Pharmaceutical Industry:
1H-INDAZOLE,3-CHLORO-7-NITROis used as a building block for the synthesis of other organic compounds. Its structural features and reactivity make it valuable for the creation of new drugs or for other synthetic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 74209-33-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,2,0 and 9 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 74209-33:
(7*7)+(6*4)+(5*2)+(4*0)+(3*9)+(2*3)+(1*3)=119
119 % 10 = 9
So 74209-33-9 is a valid CAS Registry Number.
74209-33-9Relevant articles and documents
Synthesis and biological evaluation of N-(7-indazolyl)benzenesulfonamide derivatives as potent cell cycle inhibitors
Bouissane,El Kazzouli,Leonce,Pfeiffer,Rakib,Khouili,Guillaumet
, p. 1078 - 1088 (2007/10/03)
We herein describe a new synthesis of N-(7-indazolyl)benzenesulfonamide derivatives. These compounds were evaluated for their antiproliferative activities toward L1210 murine leukemia cells. One of them, 4-methoxy-N-(3- chloro-7-indazolyl)benzenesulfonamide, was identified as the most potent with an IC50 of 0.44 μM.
Research in 7-aminoindazole series: Synthesis of new halo-7H-4-methylpyrazolo[1,5,4-ef][1,5]benzodiazepin-6-ones and 5H-9-halo-6-methylpyrazolo[1,5,4-ef][1,5]benzodiazepin-4-ones
Rakib,Benchidmi,Essassi,El Bouadili,Ibn Mansour,Bellan,Lopez,Lamande
, p. 339 - 345 (2007/10/03)
A new class of 7-aminohaloindazoles has been synthesized. Reactivity of the amino groups of these bicyclic systems has been investigated. The halogenated pyrazolo-1,5-benzodiazepinones have been synthesized by the condensation of 7-aminoindazoles with ethyl acetoacetate.