7431-77-8

Basic information

• Product Name: Sinapine thiocyanate
• Synonyms: Sinapine thiocyanate;ethanaminium, 2-\\3-(4-hydroxy-3,5-dimethoxyphenyl)-1-oxo-2-propenyl\oxy\-n,n,n-trimethyl-, thiocyanate (9ci);2-((3-(4-Hydroxy-2,5-diMethoxyphenyl)acryloyl)oxy)-N,N,N-triMethylethanaMiniuM thiocyanate;Sinapine cyanide sulfonate
• CAS NO: 7431-77-8
• Molecular Formula: C16H24NO5.CNS
• Molecular Weight: 368.452
• Mol File: 7431-77-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: Sinapine thiocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: Sinapine thiocyanate(7431-77-8)
• EPA Substance Registry System: Sinapine thiocyanate(7431-77-8)

Safety Data

• Hazardous Substances Data: 7431-77-8(Hazardous Substances Data)

Usage

Description

Sinapine thiocyanate is the thiocyanate salt form of Sinapine, an alkaloidal amine derived from black mustard seeds. It is a phenolic-choline conjugate that exhibits a range of biological activities, including anti-inflammatory, antioxidant, anti-tumor, anti-angiogenic, and radio-protective effects. As an acetylcholinesterase (AChE) inhibitor, Sinapine thiocyanate holds potential for the research and treatment of neurodegenerative diseases such as Alzheimer's, ataxia, myasthenia gravis, and Parkinson's disease.

Uses

Used in Pharmaceutical Industry:
Sinapine thiocyanate is used as a therapeutic agent for the treatment of Alzheimer's disease (AD) due to its acetylcholinesterase inhibitory properties, which can help improve cognitive function and slow down the progression of the disease.
Used in Antioxidant Applications:
Sinapine thiocyanate is used as an antioxidant in the pharmaceutical and nutraceutical industries to combat oxidative stress and protect cells from damage, potentially reducing the risk of various diseases and promoting overall health.
Used in Anti-inflammatory Applications:
Sinapine thiocyanate is used as an anti-inflammatory agent in the development of drugs targeting conditions characterized by inflammation, such as arthritis and other autoimmune disorders.
Used in Anti-tumor and Anti-angiogenic Applications:
Sinapine thiocyanate is used as an anti-tumor and anti-angiogenic agent in the research and development of cancer treatments, particularly for its potential to inhibit tumor growth and the formation of new blood vessels that supply nutrients to the tumor.
Used in Radio-protective Applications:
Sinapine thiocyanate is used as a radio-protective agent in the medical field, particularly for patients undergoing radiation therapy, to help protect healthy cells from the damaging effects of radiation and reduce the risk of side effects.