7432-25-9 Usage
Description
Etaqualone, an analog of the hypnotic methaqualone, is a non-barbiturate sedative also known as Quaalude. It is a quinazolone compound with physiological and toxicological properties that have been poorly delineated. Etaqualone is primarily intended for forensic and research applications.
Uses
Used in Forensic Applications:
Etaqualone is used as an analytical reference standard for forensic purposes, aiding in the identification and analysis of substances related to methaqualone and other similar compounds.
Used in Research Applications:
Etaqualone serves as a research tool for studying the effects and mechanisms of non-barbiturate sedatives, particularly in the context of its binding to the beta GABAA receptor and its potential role in negating insomnia.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, etaqualone is marketed as a sedative, hypnotic, muscle relaxant, and central nervous system depressant. It is used as a therapeutic agent for treating insomnia and other related conditions due to its ability to bind to the beta GABAA receptor, which helps alleviate sleep disturbances.
Check Digit Verification of cas no
The CAS Registry Mumber 7432-25-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,3 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7432-25:
(6*7)+(5*4)+(4*3)+(3*2)+(2*2)+(1*5)=89
89 % 10 = 9
So 7432-25-9 is a valid CAS Registry Number.
InChI:InChI=1/C17H16N2O/c1-3-13-8-4-7-11-16(13)19-12(2)18-15-10-6-5-9-14(15)17(19)20/h4-11H,3H2,1-2H3
7432-25-9Relevant articles and documents
Metal-free C-H methylation and acetylation of heteroarenes with PEG-400
Kudale, Vishal Suresh,Wang, Jeh-Jeng
supporting information, p. 3506 - 3511 (2020/06/25)
The generation of a methyl carbon source from renewable and cheap sources is challenging. Herein, we describe a novel and an efficient route for methylation and acetylation of aza-heteroarenes using PEG-400 under O2and TsOH·H2O for the first time by tuning the reaction conditions using a different set of starting materials. The key features of the current protocol are oxidative C-O and C-C bond scission under metal-free conditions with good functional group tolerance, and a broad substrate scope. The potential applicability of the designed methodology was demonstrated for the synthesis of central nervous system (CNS) depressant and anticonvulsant drug molecules by a one-pot strategy.
A convenient synthesis of 2-methyl-3-substituted-4(3H)-quinazolinones using bis(trichloromethyl) carbonate as condensing agent
Su,Wu,Xie,Li
, p. 89 - 94 (2007/10/03)
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