74333-44-1

Basic information

• Product Name: AMINOETHYLPHOSPHINIC ACID
• Synonyms: AMINOETHYLPHOSPHINIC ACID;1-aMinoethylphosphinic acid,Brillian-MB288
• CAS NO: 74333-44-1
• Molecular Formula: C₂H₈NO₂P
• Molecular Weight: 109.064181
• Mol File: 74333-44-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 268.2 °C at 760 mmHg
• Flash Point: 116 °C
• Appearance: /
• CAS DataBase Reference: AMINOETHYLPHOSPHINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: AMINOETHYLPHOSPHINIC ACID(74333-44-1)
• EPA Substance Registry System: AMINOETHYLPHOSPHINIC ACID(74333-44-1)

Safety Data

• Hazardous Substances Data: 74333-44-1(Hazardous Substances Data)

Usage

General Description

Aminoethylphosphinic acid (AEPA) is a chemical compound with the formula C2H8NO2P. It is a phosphinic acid, a type of organophosphorus compound. AEPA is commonly used as a chelating agent in metal ion complexation and extraction processes, as well as in applications such as water treatment and corrosion inhibition. It is also used in the synthesis of pharmaceuticals and agrochemicals. AEPA has the ability to form stable complexes with various metal ions, and its chelating properties make it useful in various industrial and research applications. Additionally, AEPA is considered to be of low toxicity and is relatively easy to handle and store, making it a versatile and valuable chemical compound.

Upstream product

• 65577-30-2 1-(benzhydrylamino)ethylphosphinic acid 
• 125402-13-3 [1-(Benzhydrylidene-amino)-ethyl]-diethoxymethyl-phosphinic acid ethyl ester 
• 62415-63-8 formylacetic acid oxime 
• 30148-50-6 bis(trimethylsilyl)phosphonite 
• 120060-76-6 Eth-(E)-ylidene-trityl-amine 
• 107-29-9 Acetaldehyde oxime 

Downstream Products

• 6323-97-3 1-aminoethanephosphonic acid 
• 108327-37-3 [1-[[(phenylmethoxy)carbonyl]amino]ethyl]phosphinic acid 
• 6323-97-3 (-)-1-aminoethylphosphonic acid 
• 145728-55-8 (L,D)-1-(N-phenylacetylamino)ethylphosphinic acid 
• 73336-73-9 C₁₃H₁₉N₂O₅P 
• 73336-74-0 C₁₃H₁₉N₂O₅P 

Relevant articles and documents

Synthesis of alkyl hydrogen (1-aminoalkyl)phosphonates

Addition of hypophosphorous acid to aldoximes affords (1-aminoalkyl) phosphinic acids which on treatment with bromine in alkanols are transformed into alkyl hydrogen (1-aminoalkyl)phosphonates.

Application of in situ silylation for improved, convenient preparation of fluorenylmethoxycarbonyl (Fmoc)-protected phosphinate amino acids

(Chemical Equation Presented) A convenient and efficient method has been developed for the preparation of 9-fluorenylmethoxycarbonyl (Fmoc)-protected 1-aminoalkylphosphinic acids. Reproducible procedures for the synthesis and purification of free α-amino H-phosphinates are provided. Protection of free amino phosphinates as the N-Fmoc derivative was achieved by in situ trimethylsilylation of aminoalkylphosphinic acids, which then reacted with Fmoc-Cl to provide corresponding products in excellent yields and in high purity after simple extractive isolation. Mechanistic aspects of the silylation are discussed, and the application of the procedure to another class of amino phosphorus acids is presented.

Inhibition of the Staphylococcus aureus sortase transpeptidase SrtA by phosphinic peptidomimetics

During pathogenesis, Gram-positive bacteria utilize surface protein virulence factors such as the MSCRAMMs (microbial surface components recognizing adhesive matrix molecules) to aid the initiation and propagation of infection through adherence to host en