74376-23-1

Basic information

• Product Name: 2-phenyl-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one
• Synonyms: 2-phenyl-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one
• CAS NO: 74376-23-1
• Molecular Weight: 278.334
• Mol File: 74376-23-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenyl-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one(74376-23-1)
• EPA Substance Registry System: 2-phenyl-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one(74376-23-1)

Safety Data

• Hazardous Substances Data: 74376-23-1(Hazardous Substances Data)

Upstream product

• 134469-07-1 Benzimidazol-2-thiol 
• 637-44-5 phenylpropyolic acid 
• 7299-58-3 phenylpropiolyl chloride 
• 583-39-1 2,3-dihydrobenzimidazol-2-thione 

Downstream Products

• 40828-54-4 1H-benzimidazole-2-sulfonic acid 
• 140-10-3 (E)-3-phenylacrylic acid 

Relevant articles and documents

N-Heterocyclic Carbene-Catalyzed in situ Activation of Alkynyl Acids for C?S Bond Formation: Access to Imidazo[2,1-b][1,3]thiazinones

Alkynyl acids are first utilized as alkynyl acylazolium precursors through an in situ activation strategy for the efficient construction of carbon-sulfur bond in a formal [3+3] annulation. This protocol offers a direct and rapid pathway for the synthesis of imidazo[2,1-b][1,3]thiazinone skeleton, a useful heterocyclic class frequently found in many bioactive compounds. This reaction also has the advantages of scalability, readily available materials, and simple manipulation in open air. (Figure presented.).