74553-29-0 Usage
Description
2,5-Dibromobenzaldehyde is an organic compound with the molecular formula C7H4Br2O. It is a brominated derivative of benzaldehyde, featuring two bromine atoms at the 2nd and 5th positions on the benzene ring. 2,5-Dibromobenzaldehyde is known for its reactivity and is commonly utilized as a building block in the synthesis of various organic molecules.
Uses
Used in Chemical Synthesis:
2,5-Dibromobenzaldehyde is used as an intermediate in the chemical synthesis industry. It serves as a key component in the production of other chemicals, contributing to the formation of a diverse range of compounds with various applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,5-Dibromobenzaldehyde is used as a precursor for the synthesis of pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential therapeutic properties.
Used in Organic Chemistry Research:
2,5-Dibromobenzaldehyde is also utilized in organic chemistry research, where it is employed to study the reactivity of brominated aromatic compounds and to develop new synthetic methods and reactions.
Used in the Synthesis of 2-(2,5-Dibromo-phenyl)-[1,3]dioxolane:
2,5-Dibromobenzaldehyde is used as a reactant in the synthesis of 2-(2,5-Dibromo-phenyl)-[1,3]dioxolane, a compound that can be obtained by reacting it with Ethane-1,2-diol. The reaction is facilitated by the use of p-toluenesulfonic acid as a reagent and toluene as a solvent. This specific application demonstrates the versatility of 2,5-Dibromobenzaldehyde in creating complex molecular structures.
Check Digit Verification of cas no
The CAS Registry Mumber 74553-29-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,5,5 and 3 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 74553-29:
(7*7)+(6*4)+(5*5)+(4*5)+(3*3)+(2*2)+(1*9)=140
140 % 10 = 0
So 74553-29-0 is a valid CAS Registry Number.
InChI:InChI=1/C7H4Br2O/c8-6-1-2-7(9)5(3-6)4-10/h1-4H
74553-29-0Relevant articles and documents
Palladium-catalyzed ortho-C(sp2)[sbnd]H bromination of benzaldehydes via a monodentate transient directing group strategy
Yong, Qiyun,Sun, Bing,Zhang, Fang-Lin
supporting information, (2019/11/03)
A facile and efficient monodentate transient directing group strategy was developed to enable the palladium-catalyzed ortho-C(sp2)[sbnd]H bromination of benzaldehydes. A broad scope of benzaldehydes were transformed into the desired products by employing 2-amino-5-chlorobenzotrifluoride as a monodentate transient directing group, demonstrating good functional group tolerance. Mild reaction conditions and no requirement for a silver salt are also features of this strategy.
A Bio-inspired Approach for Chromophore Communication: Ligand-to-Ligand and Host-to-Guest Energy Transfer in Hybrid Crystalline Scaffolds
Dolgopolova, Ekaterina A.,Williams, Derek E.,Greytak, Andrew B.,Rice, Allison M.,Smith, Mark D.,Krause, Jeanette A.,Shustova, Natalia B.
, p. 13639 - 13643 (2015/11/11)
Efficient multiple-chromophore coupling in a crystalline metal-organic scaffold was achieved by mimicking a protein system possessing 100 % energy-transfer (ET) efficiency between a green fluorescent protein variant and cytochrome b562. The two
Selective ortho -bromination of substituted benzaldoximes using Pd-catalyzed C-H activation: Application to the synthesis of substituted 2-bromobenzaldehydes
Dubost, Emmanuelle,Fossey, Christine,Cailly, Thomas,Rault, Sylvain,Fabis, Frederic
, p. 6414 - 6420 (2011/09/16)
Substituted 2-bromobenzaldehydes were synthesized from benzaldehydes using a three-step sequence involving a selective palladium-catalyzed ortho-bromination as the key step. O-Methyloxime serves as a directing group in this reaction. A rapid deprotection of substituted 2-bromobenzaldoximes afforded substituted 2-bromobenzaldehydes with good overall yields.