74571-81-6

Basic information

• Product Name: 3-bromo-2,4-dimethylphenol
• Synonyms: 3-bromo-2,4-dimethylphenol
• CAS NO: 74571-81-6
• Molecular Weight: 201.063
• Mol File: 74571-81-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-bromo-2,4-dimethylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-2,4-dimethylphenol(74571-81-6)
• EPA Substance Registry System: 3-bromo-2,4-dimethylphenol(74571-81-6)

Safety Data

• Hazardous Substances Data: 74571-81-6(Hazardous Substances Data)

Upstream product

• 105-67-9 2,4-Xylenol 
• 576-22-7 2-Bromo-m-xylene 
• 693285-59-5 3-bromo-2,4-dimethylbenzaldehyde 
• 66314-77-0 3-bromo-dimethylaniline 

Downstream Products

• 693285-60-8 2,6-dimethyl-3-methoxybenzene boronic acid 
• 23453-90-9 2-bromo-4-methoxy-1,3-dimethylbenzene 
• 23531-29-5 Dimethyl-2-brom-4-methoxy-isophthalat 
• 23453-91-0 2-Brom-4-methoxy-isophthalsaeure 
• 22955-73-3 dimethyl 4-methoxyisophthalate 

Relevant articles and documents

meta-Bromination of Phenols in Superacids

In SbF5-HF, para-alkylated or 2,6-dialkylated phenols (and their ethers) react with bromine to give the corresponding meta-bromo-substituted compounds; the mechanism implies bromination of the O-protonated substrate.

4,5-DISUBSTITUTED-2-ARYL PYRIMIDINES

4,5-disubstituted-2-arylpyrimidines of Formula (I) and Formula (II) are provided: wherein R1, R2, R3, R8, R9, A and Ar are defined herein. Such compounds are ligands of C5a receptors. Preferred compounds of Formula I and II bind to C5a receptors with high affinity and exhibit neutral antagonist or inverse activity at C5a receptors. The present invention also relates to pharmaceutical compositions comprising such compounds, and to the use of such compounds in treating a variety of inflammatory, cardiovascular, and immune system disorders. In addition, the present invention provides labeled 4,5-disubstituted-2-arylpyrimidines, which are useful as probes for the localization of C5a receptors.