7460-91-5Relevant articles and documents
Synthesis and Antineoplastic Activity of 5-N-Alkyl-2-p-substituted-benzenesulphonyl-L-glutamines
De, A. U.,Pandey, Jiten,Majumdar, Anjali
, p. 481 - 483 (2007/10/02)
5-N-Alkyl-2-p-substituted-benzenesulphonyl-l-glutamines (III) have been synthesised and their antineoplastic potency evaluated in Ehrlich ascites carcinoma (EAC) in Swiss albino mice.A few of the compounds show appreciable activity.An interesting phenomenon of C-N bond cleavage has been observed when 2-p-toluenesulphonyl-L-glutamine (III; X = CH3, R = H) is treated with PPA.