74602-32-7

Basic information

• Product Name: 5,7-DODECADIYNE-1,12-DIOL
• Synonyms: 5,7-DODECADIYNE-1,12-DIOL;5,7-DODECADIYN-1,12-DIOL;TIMTEC-BB SBB008730;5,7-DODECADIYNE-1,12-DIOL,TECHNICAL;5,7-DODECADIYN-1,12-DIOL 95%;5,7-DODECADIYN-1,12-DIOL, 95%,
• CAS NO: 74602-32-7
• Molecular Formula: C₁₂H₁₈O₂
• Molecular Weight: 194.27
• Mol File: 74602-32-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 49.5 °C
• Boiling Point: 371.8°C at 760 mmHg
• Flash Point: 178.6°C
• Appearance: /
• Density: 1.032g/cm³
• Vapor Pressure: 4.81E-07mmHg at 25°C
• Refractive Index: 1.514
• PKA: 14.72±0.10(Predicted)
• BRN: 1757614
• CAS DataBase Reference: 5,7-DODECADIYNE-1,12-DIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-DODECADIYNE-1,12-DIOL(74602-32-7)
• EPA Substance Registry System: 5,7-DODECADIYNE-1,12-DIOL(74602-32-7)

Safety Data

• Safety Statements: 22-24/25
• Hazardous Substances Data: 74602-32-7(Hazardous Substances Data)

Usage

General Description

5,7-Dodecadiyne-1,12-diol is a chemical compound with the molecular formula C12H20O2. It is a diol, meaning it contains two hydroxyl (-OH) functional groups, and it also contains a triple bond between carbon atoms. 5,7-Dodecadiyne-1,12-diol is used in organic synthesis as a building block for the production of various organic compounds and materials. It is also used in the development of new pharmaceuticals and in research as a reagent for chemical reactions. 5,7-Dodecadiyne-1,12-diol has potential applications in a wide range of industries, including pharmaceuticals, materials science, and chemical manufacturing.

InChI:InChI=1/C12H18O2/c13-11-9-7-5-3-1-2-4-6-8-10-12-14/h13-14H,5-12H2

Upstream product

• 928-90-5 5-hexyl-1-ol 
• 615-42-9 1,2-Diiodobenzene 
• 392-57-4 1,4-diiodo-2,3,5,6-tetrafluorobenzene 

Downstream Products

• 130562-02-6 5,7-dodecacadiyn-1,12-ylene di(1,2-diphenylcycloprpene-3-carboxylate) 
• 1363157-35-0 5,7-decadiyne-1,12-diyl bis[N-(3,4,5-trimethoxyphenyl)carbamate] 
• 1363157-34-9 5,7-decadiyne-1,12-diyl bis[N-(3,4,5-tridodecyloxyphenyl)carbamate] 
• 28393-04-6 dodeca-5,7-diynedioic acid 

Relevant articles and documents

Synthesis and Evaluation of a Series of Bis(pentylpyridinium) Compounds as Antifungal Agents

A series of bis(4-pentylpyridinium) compounds with a variety of spacers between the pyridinium headgroups was synthesised, and the antifungal activity of these compounds was investigated. Lengthening the alkyl spacer between the pentylpyridinium headgroups from 12 to 16 methylene units resulted in increased antifungal activity against C. neoformans and C. albicans, but also resulted in increased hemolytic activity and cytotoxicity against mammalian cells. However, inclusion of an ortho-substituted benzene ring in the centre of the alkyl spacer resulted in decreased cytotoxicity and hemolytic activity, while maintaining antifungal potency. Replacement of the alkyl and aromatic-containing spacers by more hydrophilic ethylene glycol groups resulted in a loss of antifungal activity. Some of the compounds inhibited fungal PLB1 activity, but the low correlation of this inhibition with antifungal potency indicates PLB1 inhibition is unlikely to be the predominant mode of antifungal action of this class of compounds, with preliminary studies suggesting they may act via disruption of fungal mitochondrial function.