7483-59-2 Usage
Description
3-(1-Piperazinyl)-1,2-propanediol is a chemical compound that features a piperazine ring and a propanediol group. It is widely recognized for its role as a pharmaceutical intermediate, playing a crucial part in the synthesis of a range of medications, particularly those used for treating mental health conditions such as antipsychotic and antidepressant drugs. 3-(1-Piperazinyl)-1,2-propanediol is also valued for its capacity to improve the solubility and absorption of certain drugs, thereby enhancing their efficacy within the body. Moreover, it has been the subject of research for its potential therapeutic applications in treating anxiety disorders and irritable bowel syndrome, making it a significant entity in the realm of pharmaceutical research and development.
Uses
Used in Pharmaceutical Industry:
3-(1-Piperazinyl)-1,2-propanediol is used as a pharmaceutical intermediate for the synthesis of various drugs, particularly antipsychotic and antidepressant medications. Its presence in these formulations aids in enhancing the solubility and absorption of the drugs, which is essential for improving their therapeutic effects.
Used in Drug Formulation:
3-(1-Piperazinyl)-1,2-propanediol is utilized in drug formulations to improve the solubility and absorption of certain medications. This enhancement is critical for the drugs' effectiveness, as it allows for better bioavailability and therapeutic action within the body.
Used in Medical Research:
3-(1-Piperazinyl)-1,2-propanediol is used in medical research for exploring its potential applications in treating various conditions, including anxiety disorders and irritable bowel syndrome. Its unique structure and properties make it a promising candidate for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 7483-59-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,8 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7483-59:
(6*7)+(5*4)+(4*8)+(3*3)+(2*5)+(1*9)=122
122 % 10 = 2
So 7483-59-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H16N2O2/c10-6-7(11)5-9-3-1-8-2-4-9/h7-8,10-11H,1-6H2
7483-59-2Relevant articles and documents
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Braun,Krauth
, p. 113,127 (1978)
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METHOD FOR PRODUCING HYDROXYALKYLTRIETHYLENEDIAMINE HAVING IMPROVED HUE
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Paragraph 0046; 0047, (2017/12/12)
PROBLEM TO BE SOLVED: To provide a production method which makes it possible to improve the hue of a cyclic alkanolamine such as a hydroxyalkyltriethylenediamine and efficiently obtain a high-purity bicyclic compound. SOLUTION: A method for producing the bicyclic diamine includes bringing a crude hydroxyalkyltriethylenediamine reaction liquid comprising a hydroxyalkyltriethylenediamine represented by formula (1) into contact with oxygen at 110-170°C and then distilling and purifying it (R1-R10 independently represent H, a C1-4 alkyl group or a C1-4 hydroxyalkyl group). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
The method of manufacturing the amine compound Bicylic
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Paragraph 0055; 0056, (2017/04/19)
PROBLEM TO BE SOLVED: To provide a method for simply obtaining a bicyclic amine compound at high yield and for suppressing by-product tar contents that may obstruct the continuous production. SOLUTION: The compound indicated by a formula (1) is subjected to intramolecular dehydration in a gas phase under the presence of a solid catalyst to produce the bicyclic amine compound indicated by a formula (2). In the formula (1), R1-R8each independently represents a hydrogen atom, a 1-4C alkyl group, a hydroxy group, a hydroxymethyl group or a 1-4C alkoxy group; X represents a carbon atom or a nitrogen atom; and Y represents a hydrogen atom, an alkyl group, a hydroxy group or a 1-4C hydroxyalkyl group. In the formula (2), R1-R8, X and Y are defined in the same manner as above. COPYRIGHT: (C)2012,JPOandINPIT
