74915-06-3Relevant articles and documents
STUDIES DIRECTED TOWARD SYNTHESIS OF QUASSINOIDS VII .- CONVERSION OF CHENODEOXYCHOLIC ACID TO A δ-LACTONE QUASSINOID ANALOG AND GENERATION OF A-RING DIOSPHENOL ACETATE DERIVATIVES OF DEOXYCHOLIC ACID
Dias, Jerry Ray,Nassim, Bahman
, p. 405 - 418 (1980)
Chenodeoxycholic acid was converted to a new 5,14-epi-28,30-dinorquassinoid analog.Two isomeric A-ring diosphenol acetate derivatives of deoxycholic acid were synthesized.A 3-oxo-5β-steroid was transformed to a 4-acetoxy-3-oxo-Δ4-steroid by treatment with base and oxygen or to a 2-acetoxy-3-oxo-Δ2-steroid by reaction with cupric chloride in refluxing acetic acid followed by acetylation.Ketene extrusion is a characteristic mass spectral fragmentation of these diosphenol acetates.