749216-03-3

Basic information

• Product Name: 3-{5-amino-4-[4-(4-chloro-phenyl)-thiazol-2-yl]-3-oxo-2,3-dihydro-pyrrol-1-yl}-benzoic acid
• Synonyms: 3-{5-amino-4-[4-(4-chloro-phenyl)-thiazol-2-yl]-3-oxo-2,3-dihydro-pyrrol-1-yl}-benzoic acid
• CAS NO: 749216-03-3
• Molecular Weight: 411.868
• Mol File: 749216-03-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{5-amino-4-[4-(4-chloro-phenyl)-thiazol-2-yl]-3-oxo-2,3-dihydro-pyrrol-1-yl}-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{5-amino-4-[4-(4-chloro-phenyl)-thiazol-2-yl]-3-oxo-2,3-dihydro-pyrrol-1-yl}-benzoic acid(749216-03-3)
• EPA Substance Registry System: 3-{5-amino-4-[4-(4-chloro-phenyl)-thiazol-2-yl]-3-oxo-2,3-dihydro-pyrrol-1-yl}-benzoic acid(749216-03-3)

Safety Data

• Hazardous Substances Data: 749216-03-3(Hazardous Substances Data)

Upstream product

• 99-05-8 meta-aminobenzoic acid 
• 428512-63-4 4-chloro-2-[4-(4-chloro-phenyl)-thiazol-2-yl]-3-oxo-butyronitrile 

Relevant articles and documents

Chemoselective alkylation of 3- and 4-(5-amino-4-hetaryl-2,3-dihydro-3- oxopyrrol-1-yl)benzoic acids

Alkylation of 3- and 4-(5-amino-4-hetaryl-2,3-dihydro-3-oxopyrrol-1-yl) benzoic acids with phenacyl bromides or chloroacetanilides in DMF in the presence of triethylamine occurs at the carboxy group with high selectivity and yields the corresponding phenacyl and arylcarbamoylmethyl esters. The initial pyrrolylbenzoic acids were synthesized by reaction of 3- and 4-aminobenzoic acids with 4-chloro-2-hetaryl-3-oxo-butyronitriles.