74944-82-4Relevant articles and documents
Total synthesis of balanol: a potent protein kinase C inhibitor of fungal origin
Adams, C. P.,Fairway, S. M.,Hardy, C. J.,Hibbs, D. E.,Hursthouse, M. B.,et al.
, p. 2355 - 2362 (2007/10/02)
The total synthesis of the fungal metabolite balanol, a potent inhibitor of protein kinase C, is described.The synthesis includes a novel synthesis of 3-amino-4-hydroxyazepanes via a directed ring expansion of 3-bromopiperidin-4-ones.