749849-14-7 Usage
General Description
6-Bromoimidazo[1,2-a]pyridine-2-carboxylic acid is a chemical compound with the molecular formula C8H5BrN3O2. It is a heterocyclic organic compound containing a pyridine ring fused to an imidazole ring with a carboxylic acid group attached. It has potential applications in pharmaceutical research and drug development, particularly in the synthesis of new drugs targeting specific biological pathways. 6-BROMOIMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID may have antimicrobial and antifungal properties and is used as a building block in the synthesis of various pharmaceutical drugs. Additionally, it may also have potential as a corrosion inhibitor and as a reagent in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 749849-14-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,9,8,4 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 749849-14:
(8*7)+(7*4)+(6*9)+(5*8)+(4*4)+(3*9)+(2*1)+(1*4)=227
227 % 10 = 7
So 749849-14-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2O2/c9-5-1-2-7-10-6(8(12)13)4-11(7)3-5/h1-4H,(H,12,13)
749849-14-7Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS
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, (2019/06/11)
The compounds of Formula I, Formula Ia, and Formula Ib are described herein along with their analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts, pharmaceutical compositions, metabolites, and prodrugs thereof. These compounds inhibit PRMT5 and are useful as therpeautic or ameliorating agent for diseases that are involved in cellular growth such as malignant tumors, schizophrenia, Alzheimer's disease, Parkinson's disease and the like.
A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors
Warshakoon, Namal C.,Wu, Shengde,Boyer, Angelique,Kawamoto, Richard,Sheville, Justin,Renock, Sean,Xu, Kevin,Pokross, Matthew,Evdokimov, Artem G.,Walter, Richard,Mekel, Marlene
, p. 5598 - 5601 (2007/10/03)
Utilizing modeling information from a recently resolved structure of human HIF-1α prolyl hydroxylase (EGLN1) and structure-based design, a novel series of imidazo[1,2-a]pyridine derivatives was prepared. The activity of these compounds was determined in a