74988-49-1

Basic information

• Product Name: N-Benzo[4,5]furo[3,2-d]pyrimidin-4-yl-4-methyl-benzenesulfonamide
• CAS NO: 74988-49-1
• Molecular Weight: 339.375
• Mol File: 74988-49-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-Benzo[4,5]furo[3,2-d]pyrimidin-4-yl-4-methyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Benzo[4,5]furo[3,2-d]pyrimidin-4-yl-4-methyl-benzenesulfonamide(74988-49-1)
• EPA Substance Registry System: N-Benzo[4,5]furo[3,2-d]pyrimidin-4-yl-4-methyl-benzenesulfonamide(74988-49-1)

Safety Data

• Hazardous Substances Data: 74988-49-1(Hazardous Substances Data)

Upstream product

• 49679-19-8 4-Aminobenzofuro<3,2-d>pyrimidine 
• 98-59-9 p-toluenesulfonyl chloride 
• 62208-67-7 3-amino[1]benzofuran-2-carbonitrile 
• 74988-37-7 3-(Ethoxymethylene)amino-2-benzofurancarbonitrile 

Relevant articles and documents

Dimroth Rearrangement and Other Investigations on Benzofuropyrimidines

Synthesis of 3-alkyl- and 3-aryl-3,4-dihydro-4-iminobenzofuropyrimidines (IV-IX) by the reaction of 3-(ethoxymethylene)amino-2-benzofurancarbonitrile (II) with alkyl- and aryl-amines, and their Dimroth type rearrangement to 4-alkyl- and 4-aryl-aminobenzofuropyrimidines (X-XIV) are described.The reactions of II with ammonia and hydrazine hydrate giving 4-aminobenzofuropyrimidine (III) and 3-amino-4-imino-3,4-dihydrobenzofuropyrimidine (XV) respectively have been investigated.Conversion of XV into s-triazolopyrimidobenzofuran (XVI) and 3-amino-2-benzofurancarbonitrile (I) into various 2-alkyl-4-alkoxybenzofuropyrimidines (XVII-XX) is also reported.