7500-91-6

Basic information

• Product Name: methyl 1-methyl-2-oxocyclohexanecarboxylate
• Synonyms: Methyl 1-methyl-2-oxocyclohexanecarboxylate
• CAS NO: 7500-91-6
• Molecular Formula: C₉H₁₄O₃
• Molecular Weight: 170.2057
• Mol File: 7500-91-6.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 234.3°C at 760 mmHg
• Flash Point: 95.6°C
• Density: 1.07g/cm³
• Vapor Pressure: 0.0532mmHg at 25°C
• Refractive Index: 1.457
• CAS DataBase Reference: methyl 1-methyl-2-oxocyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-methyl-2-oxocyclohexanecarboxylate(7500-91-6)
• EPA Substance Registry System: methyl 1-methyl-2-oxocyclohexanecarboxylate(7500-91-6)

Safety Data

• Hazardous Substances Data: 7500-91-6(Hazardous Substances Data)

Usage

Description

Methyl 1-methyl-2-oxocyclohexanecarboxylate is a chemical compound with the molecular formula C9H14O3. It is a derivative of cyclohexanecarboxylic acid and is used in the pharmaceutical and chemical industries as a building block for the synthesis of various compounds. It is a colorless to pale yellow liquid with a fruity odor.

Uses

Used in Flavoring Industry:
Methyl 1-methyl-2-oxocyclohexanecarboxylate is used as a flavoring agent for its fruity odor, enhancing the taste and aroma of food products.
Used in Pharmaceutical Industry:
Methyl 1-methyl-2-oxocyclohexanecarboxylate is used as an intermediate in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs.
Used in Agricultural Chemicals:
Methyl 1-methyl-2-oxocyclohexanecarboxylate is used as an intermediate for the production of insecticides and herbicides, helping to control pests and weeds in agriculture.
Used in Fragrance Industry:
Methyl 1-methyl-2-oxocyclohexanecarboxylate is used in the manufacturing of fragrances, perfumes, and other personal care products, adding a pleasant scent and enhancing the overall appeal of these products.

Upstream product

• 41302-34-5 2-(methoxycarbonyl)cyclohexanone 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 124-38-9 carbon dioxide 
• 19980-33-7 6-methyl-1-trimethylsiloxycyclohex-1-ene 
• 135482-23-4 methyl 2-iodo-2-methyl-3-oxohept-6-enoate 
• 100569-99-1 ((1R,4S)-7,7-Dimethyl-2-oxo-bicyclo[2.2.1]hept-1-yl)-methanesulfonate(R)-(4-chloro-phenyl)-ethyl-methyl-sulfonium; 
• 112818-12-9 methyl 1-(iodomethyl)-2-oxocyclohexane-1-carboxylate 
• 112211-75-3 methyl 2-oxo-1-((phenylseleno)methyl)cyclohexane-1-carboxylate 
• 67-56-1 methanol 
• 86210-70-0 methyl 2-methyl-3-oxo-hept-6-enoate 
• 19980-35-9 1-trimethylsilyloxy-2-methyl-1-cyclohexene 
• 107-46-0 Hexamethyldisiloxane 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 

Downstream Products

• 127759-60-8 methyl 1-hydroxy-6-methylcyclohexene-6-carboxylate 1-triflate 
• 90414-70-3 2-hydroxymethyl-2-methyl-cyclohexanol 
• 59416-90-9 methyl 3-methyl-2-oxocyclohexane-1-carboxylate 
• 73611-76-4 1-Methyl-2-oxo-cyclohex-3-enecarboxylic acid methyl ester 
• 124182-97-4 methyl 3-bromo-1-methyl-2-oxo-3-cyclohexenecarboxylate 
• 106334-32-1 3a-methyl-4,5,6,7-tetrahydrobenzo[c]isoxazol-3(3aH)-one 
• 106334-33-2 2-methyl-2-carbomethoxycyclohexanone oxime 
• 124182-95-2 methyl 3-bromo-1-methyl-2-oxocyclohexanecarboxylate 
• 124182-96-3 methyl 3,3-dibromo-1-methyl-2-oxocyclohexanecarboxylate 
• 58488-01-0 2-(acetoxymethyl)-2-methylcyclohexanone 
• 124183-02-4 6-(acetoxymethyl)-6-methylcyclohex-2-enone 
• 95-48-7 ortho-cresol 
• 104023-17-8 2-bromo-6-methyl-2-cyclohexen-1-one 
• 124182-94-1 6-(acetoxymethyl)-6-methyl-2,4-cyclohexadien-1-one 

Relevant articles and documents

Organic dye-catalyzed radical ring expansion reaction

Herein, we reported an attractive method for synthesizing medium-sized rings that are catalyzed by erythrosine B under fluorescent light irradiation. This synthetic approach featured mild conditions, a facile procedure, a broad substrate scope, and modera

Cyclizations of unsaturated CR(COX)2 radicals. Manganese(III) acetate oxidative cyclizations of unsaturated acetoacetates and atom-transfer cyclizations of unsaturated haloacetoacetates give the same radicals

Comparable regio- and stereochemical results were obtained when cyclizations of a series of 2-substituted 3-oxohept-6-enoate (or oct-7-enoate) esters (acetoacetates) were conducted by manganese(III) acetate oxidation or by iodine or bromine atom transfer

Asymmetric Alkylation of β-Keto Esters with Optically Active Sulfonium Salts

Alkylation of the cyclic β-keto ester2-(methoxycarbonyl)-1-indanone (2) with racemic alkylsulfonium salts 1a-h gave 2-alkylindanones 3 and 4 in 60-96percent yields.The relative reactivities of the alkyl substituents of aryldialkylsulfonium salts 1e and 1f were quite different from those in SN2 alkylations.Asymmetric induction occured upon alkylation of 2 with optically active sulfonium salts. (R)-2-Ethyl-2-(methoxycarbonyl)cyclohexanone (11) was obtained in up to 16percent ee by alkylation of the enolate ion of 2-(methoxycarbonyl)cyclohexanone (9) with optically active (R)-(+)-(p-chlorophenyl)ethylmethylsulfonium d-10-camphorsulfonate (1k).Alkylation of the enolate ion of 2 with sulfonium salts containing optically active alkyl groups afforded C-alkylated products with inversion of configuration at the asymmetric alkyl carbon atom.These alkylations appear to proceed via an S-O sulfurane intermediate or a tight ion pair with subsequent stereoselective alkyl migration to the enolate.