75032-27-8Relevant articles and documents
STRAD-BINDING AGENTS AND USES THEREOF
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Paragraph 0772-0774, (2021/08/06)
Disclosed herein, inter alia, are compounds for binding STRAD pseudokinase and uses thereof.
Rhodium-Catalyzed Rearrangement of S/Se-Ylides for the Synthesis of Substituted Vinylogous Carbonates
Reddy, Angula Chandra Shekar,Anbarasan, Pazhamalai
supporting information, p. 9965 - 9969 (2019/12/24)
An efficient rhodium-catalyzed unprecedented oxa-[2,3]-sigmatropic rearrangement of sulfur ylide derived from α-thioesters/ketones and diazo carbonyl compounds has been accomplished for the synthesis of various sulfur-tethered vinylogous carbonates in good to excellent yields. Important features of the developed reaction include wide functional group tolerance, excellent chemo- and regioselectivity, and efficient rearrangement involving the carbonyl motif. The present reaction also equally works well with α-selenoesters for the synthesis of seleno-containing vinylogous carbonates.
Synthesis of thioether andrographolide derivatives and their inhibitory effect against cancer cells
Liu, Yi,Liang, Ren-Ming,Ma, Qing-Ping,Xu, Kai,Liang, Xin-Yong,Huang, Wei,Sutton, Robert,Ding, Jie,O'Neil, Paul M.,Cheng, Chun-Ru
, p. 1268 - 1274 (2017/07/07)
A series of novel thioether andrographolide derivatives were synthesized by incorporating various aromatic (or heteroaromatic) substituents into C-12 or 14-OH. A total of 38 andrographolide derivatives were prepared and evaluated for their in vitro inhibi
