75152-18-0

Basic information

• Product Name: 5(4H)-Oxazolone, 2-(4-methylphenyl)-
• CAS NO: 75152-18-0
• Molecular Formula: C10H9NO2
• Molecular Weight: 175.187
• Mol File: 75152-18-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5(4H)-Oxazolone, 2-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4H)-Oxazolone, 2-(4-methylphenyl)-(75152-18-0)
• EPA Substance Registry System: 5(4H)-Oxazolone, 2-(4-methylphenyl)-(75152-18-0)

Safety Data

• Hazardous Substances Data: 75152-18-0(Hazardous Substances Data)

Upstream product

• 27115-50-0 N-(4-methylbenzoyl)glycine 
• 75152-14-6 (4-Methyl-benzoylamino)-acetic acid 4-nitro-phenyl ester 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 72615-38-4 (4Z)-2-(4-methylphenyl)-4-(phenylmethylidene)-1,3-oxazol-5(4H)-one 
• 107871-15-8 4-ethylidene-2-p-tolyl-4H-oxazol-5-one 
• 21336-76-5 4-[2-(1-methyl-1H-naphtho[1,2-d]oxazol-2-ylidene)-ethylidene]-2-p-tolyl-4H-oxazol-5-one 
• 21335-22-8 4-[2-(3-methyl-3H-naphtho[2,1-d]oxazol-2-ylidene)-ethylidene]-2-p-tolyl-4H-oxazol-5-one 
• 1206981-95-4 2-(2-(p-tolyl)oxazol-5-yl)acetonitrile 
• 1355332-97-6 ethyl 2-(2-(p-tolyl)oxazol-5-yl)acetate 
• 1360824-98-1 (1R,3aS,6aR)-4,6-dioxo-3-(4-methylphenyl)-5-phenyl-1,3a,4,5,6,6a-hexahydropyrrolo[3,4-c]pyrrole-1-carboxylic acid methyl ester 
• 96907-63-0 2,5-bis-(4-methylphenyl)oxazole 
• 16155-60-5 5-phenyl-2-p-tolyloxazole 
• 82221-14-5 4-Methyl-N-[1-(2-oxo-2-phenylethyl)]benzamide 
• 96907-78-7 4-methyl-N-(2-oxo-2-(4-methylphenyl)ethyl)benzamide 
• 27115-50-0 N-(4-methylbenzoyl)glycine 

Relevant articles and documents

One-pot synthesis of 2,4,5-trisubstituted oxazoles from N-acyl amino acids by a combination of cyclodehydration with N,N′-diisopropylcarbodiimide and Wittig olefination

By a combination of cyclodehydration of N-acyl amino acids with N,N′-diisopropylcarbodiimide (DIC) and non-classical Wittig olefination of the resultant 5(4H)-oxazolones with Ph3PCHCN and Ph 3PCHCOOEt, 5-oxazoleacetonitriles and 5-oxazoleacetates were synthesized in one-pot in 41-85% and 57-70% yields, respectively.