75159-10-3

Basic information

• Product Name: 4-METHYL-N-(4-METHYL-BENZYLIDENE)-BENZENESULFONAMIDE
• Synonyms: 4-METHYL-N-(4-METHYL-BENZYLIDENE)-BENZENESULFONAMIDE;N-(4-Methylbenzylidene)-4-MethylbenzenesulfonaMide
• CAS NO: 75159-10-3
• Molecular Formula: C₁₅H₁₅NO₂S
• Molecular Weight: 273.35
• Mol File: 75159-10-3.mol
• Article Data: 98

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-METHYL-N-(4-METHYL-BENZYLIDENE)-BENZENESULFONAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-N-(4-METHYL-BENZYLIDENE)-BENZENESULFONAMIDE(75159-10-3)
• EPA Substance Registry System: 4-METHYL-N-(4-METHYL-BENZYLIDENE)-BENZENESULFONAMIDE(75159-10-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• Hazardous Substances Data: 75159-10-3(Hazardous Substances Data)

Upstream product

• 63609-88-1 9-fluorenethione S-p-toluenesulfomimide 
• 4702-76-5 N-[1-p-Tolyl-meth-(Z)-ylidene]-N'-[1-p-tolyl-meth-(E)-ylidene]-hydrazine 
• 104-87-0 4-methyl-benzaldehyde 
• 101359-08-4 N-tosyltriphenylbismuthimine 
• 73844-91-4 (2S,3S)-2-(Toluene-4-sulfonyl)-3-p-tolyl-oxaziridine 
• 2403-59-0 p-(diethoxymethyl)toluene 
• 70-55-3 toluene-4-sulfonamide 
• 603-35-0 triphenylphosphine 
• 163926-84-9 4-Methyl-N-[2-p-tolyl-1λ⁴-naphtho[1,8-de][1,3]dithiin-(1E)-ylidene]-benzenesulfonamide 
• 1058-14-6 N-p-tolylsulfonylphosphine imide 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 852919-31-4 (Z)-1-chloro-4-phenylbut-1-en-1-yl acetate 
• 10504-92-4 N-p-xylyl-p-toluenesulfonamide 
• 127-65-1 chloroamine-T 

Downstream Products

• 73844-91-4 (2S,3S)-2-(Toluene-4-sulfonyl)-3-p-tolyl-oxaziridine 
• 94771-84-3 2-[(Toluene-4-sulfonylamino)-p-tolyl-methyl]-acrylic acid ethyl ester 
• 10504-92-4 N-p-xylyl-p-toluenesulfonamide 

Relevant articles and documents

Copper-boryl mediated transfer hydrogenation of N-sulfonyl imines using methanol as the hydrogen donor

B2Pin2-assisted copper-catalyzed transfer hydrogenation of aromatic sulfonylimines has been achieved, delivering a variety of aryl/heteroaryl sulfonamides in good to excellent yields under mild reaction conditions and with methanol a

Palladium-Catalyzed Regioselective and Stereospecific Ring-Opening Suzuki-Miyaura Arylative Cross-Coupling of 2-Arylazetidines with Arylboronic Acids

We have developed a palladium-catalyzed regioselective and enantiospecific ring-opening Suzuki–Miyaura arylative cross-coupling of N-tosyl-2-arylazetidines to give enantioenriched 3,3-diarylpropylamines. This reaction represents an example of transition-metal-catalyzed ring-opening cross-coupling using azetidines as a non-classical alkyl electrophile. Density functional theory rationalized the mechanism of the full catalytic cycle, which consists of the selectivity-determining ring opening of the azetidine, reaction with water, rate-determining transmetalation, and reductive elimination. Transition states of the selectivity-determining ring-opening step were systematically determined by the multi-component artificial force induced reaction (MC-AFIR) method to explain the regioselectivity of the reaction. (Figure presented.).

Chiral-Directing-Group-Assisted Rhodium(III)-Catalyzed Asymmetric Addition of Inert Arene C?H Bond to Aldimines with Subsequent Intramolecular Cyclization

By using a chiral directing group, an asymmetric rhodium(III)-catalyzed C?H bond addition to aldimines followed by intramolecular cyclization to form chiral isoindolinones has been achieved (up to 68 % yield, up to 93 % ee). A three-component variant that resembles Mannich reaction was also realized (41 % yield, 83 % ee). Product elaborations and preliminary mechanistic studies were described.