75414-09-4

Basic information

• Product Name: 6-trifluoromethyl-5,6,7,8-tetrahydroquinoline
• CAS NO: 75414-09-4
• Molecular Weight: 201.191
• Mol File: 75414-09-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-trifluoromethyl-5,6,7,8-tetrahydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6-trifluoromethyl-5,6,7,8-tetrahydroquinoline(75414-09-4)
• EPA Substance Registry System: 6-trifluoromethyl-5,6,7,8-tetrahydroquinoline(75414-09-4)

Safety Data

• Hazardous Substances Data: 75414-09-4(Hazardous Substances Data)

Upstream product

• 325-13-3 6-(trifluoromethyl) quinolone 

Relevant articles and documents

Selectivity in the Hydrogenation of 6- and 8-Substituted-quinolines

Quinoline (1) and the 6- or 8-substituted-quinolines (2)-(14) (R = Me, Pri, But, Ph, OMe, OH, CF3, or F) were hydrogenated catalytically on platinum under either weakly basic (solvent MeOH) or strongly acidic (solvent CF3CO2H) conditions.In methanol the only product was the corresponding 1,2,3,4-tetrahydro-compound.In trifluoroacetic acid, compounds hydrogenated in the benzene ring were isolated as major products; both electron-withdrawing and electron-donating substituents at C-6 or C-8 cause (sometimes drastic) reduction in yield.The products were characterized by their 1H and 13C n.m.r. spectra.