75792-66-4

Basic information

• Product Name: 3-chloro-6-(2-methyl-1H-imidazol-1-yl)pyridazine(SALTDATA: FREE)
• Synonyms: 3-chloro-6-(2-methyl-1H-imidazol-1-yl)pyridazine(SALTDATA: FREE);3-chloro-6-(2-methyl-1H-imidazol-1-yl)pyridazine
• CAS NO: 75792-66-4
• Molecular Formula: C₈H₇ClN₄
• Molecular Weight: 194.62098
• Mol File: 75792-66-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-chloro-6-(2-methyl-1H-imidazol-1-yl)pyridazine(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-6-(2-methyl-1H-imidazol-1-yl)pyridazine(SALTDATA: FREE)(75792-66-4)
• EPA Substance Registry System: 3-chloro-6-(2-methyl-1H-imidazol-1-yl)pyridazine(SALTDATA: FREE)(75792-66-4)

Safety Data

• Hazardous Substances Data: 75792-66-4(Hazardous Substances Data)

Upstream product

• 141-30-0 3,6-dichlorpyridazine 
• 693-98-1 2-methylimidazole 

Downstream Products

• 75792-67-5 3-hydrazino-6-(2-methyl-imidazol-1-yl)-pyridazine 
• 75792-85-7 3-(2-isopropylidene-hydrazino)-6-(2-methyl-imidazol-1-yl)-pyridazine 

Relevant articles and documents

Cardiotonic agents. 7. Inhibition of separated forms of cyclic nucleotide phosphodiesterase from guinea pig cardiac muscle by 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds. Structure-activity relationships and correl

The structure-activity relationships of a series of 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds were investigated for the in vivo inhibition of different forms of cyclic nucleotide phosphodiesterase (PDE) isolated

Synthesis and antihypertensive activity of new 6-heteroaryl-3-hydrazinopyridazine derivatives

The synthesis and pharmacological activity of new 6-heteroaryl-3-hydrazinopyridazines with antihypertensive action are described. The introduction of pyrrole, pyrazole, imidazole, triazole, tetrazole, thiophene, indole, and carbazole heterocyclic rings into the 6 position of the pyridazine nucleus has been carried out by three different methods of synthesis. The hypotensive action has been examined on normotensive and spontaneously hypertensive rats by comparison with dihydralazine (I). 6-Imidazol-1-yl derivatives have proved particularly active. Of these derivatives 3-hydrazino-6-(2-methylimidazol-1-yl)pyridazine (7c) achieves 4.9 times the activity of dihydralazine when administered orally to spontaneously hypertensive rats. The LD50 values of 7c and dihydralazine are very similar.