75814-58-3Relevant articles and documents
Nickel-Catalyzed Decarboxylative Alkenylation of Anhydrides with Vinyl Triflates or Halides
Chen, Hui,Sun, Shuhao,Liao, Xuebin
supporting information, p. 3625 - 3630 (2019/05/24)
Decarboxylative cross-coupling of aliphatic acid anhydrides with vinyl triflates or halides was accomplished via nickel catalysis. This methodology works well with a broad array of substrates and features abundant functional group tolerance. Notably, our approach addresses the issue of safe and environmental installation of methyl or ethyl group into molecular scaffolds. The method possesses high chemoselectivity toward alkyl groups when aliphatic/aromatic mixed anhydrides are involved. Furthermore, diverse ketones could be modified with our strategy.
Syntheses of the Macrocyclic Spermine Alkaloids (+/-)-Budmunchiamine A-C
Popaj, Kasim,Hesse, Manfred
, p. 180 - 186 (2007/10/03)
The syntheses of four macrocyclic spermine alkaloids, (+/-)-budmunchiamine A-C (1a-c) and (+/-)-budmunchiamine L4 (1), were accomplished by Michael addition of spermine to the α,β-unsaturated esters 3a-d, followed by cyclization of the resulting α,ω-tetraamino esters 4a-d with triethoxyantimony; N-methylation of the amino lactams 6a-c yielded the budmunchiamines A-C (1a-c).
