760-94-1

Basic information

• Product Name: DIMETHYL A-BROMOGLUTARATE
• Synonyms: DIMETHYL A-BROMOGLUTARATE;Dimethyl alpha-bromoglutarate;NISTC760941;2-bromoglutaric acid dimethyl ester;dimethyl 2-bromopentanedioate;Dimethyl 2-bromoglutarate;Dimethyl A-Bromoglutarate(WXC00462)
• CAS NO: 760-94-1
• Molecular Formula: C₇H₁₁BrO₄
• Molecular Weight: 239.06
• Mol File: 760-94-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 135℃ (11 Torr)
• Flash Point: 99.1±23.2℃
• Appearance: /
• Density: 1.452±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.0382mmHg at 25°C
• Refractive Index: 1.4631 (589.3 nm 20℃)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: DIMETHYL A-BROMOGLUTARATE(CAS DataBase Reference)
• NIST Chemistry Reference: DIMETHYL A-BROMOGLUTARATE(760-94-1)
• EPA Substance Registry System: DIMETHYL A-BROMOGLUTARATE(760-94-1)

Safety Data

• Hazardous Substances Data: 760-94-1(Hazardous Substances Data)

Usage

Description

DIMETHYL A-BROMOGLUTARATE, with the chemical formula C7H11BrO4, is an organic compound that exists as a colorless liquid. As an ester, it is formed through the reaction of an alcohol and an organic acid. DIMETHYL A-BROMOGLUTARATE is primarily utilized as a building block in the synthesis of various pharmaceuticals and fine chemicals, and is also employed as a reagent in organic chemistry reactions due to its ability to undergo nucleophilic substitution reactions. It is crucial to handle and store DIMETHYL A-BROMOGLUTARATE with care, considering its flammable nature and potential hazards.

Uses

Used in Pharmaceutical and Fine Chemicals Synthesis:
DIMETHYL A-BROMOGLUTARATE is used as a building block for the synthesis of various pharmaceuticals and fine chemicals. Its unique chemical structure allows it to be a valuable component in creating a wide range of products with specific therapeutic or functional properties.
Used in Organic Chemistry Reactions:
DIMETHYL A-BROMOGLUTARATE is used as a reagent in organic chemistry reactions, particularly for its ability to undergo nucleophilic substitution reactions. This makes it a useful tool for chemists in developing new compounds and advancing research in organic chemistry.
Used in Research and Development:
Due to its reactivity and unique properties, DIMETHYL A-BROMOGLUTARATE is used in research and development settings to explore new chemical reactions and syntheses. This can lead to the discovery of novel compounds and applications in various industries, including pharmaceuticals, materials science, and more.

InChI:InChI=1/C7H11BrO4/c1-11-6(9)4-3-5(8)7(10)12-2/h5H,3-4H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 1501-26-4 methyl 4-(chlorocarbonyl)butyrate 

Downstream Products

• 82111-66-8 phenylthio-2 glutarate de methyle 
• 103301-78-6 1-benzyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 180629-35-0 5-(hydroxymethyl)-1-(4-methoxyphenyl)pyrrolidin-2-one 
• 180629-37-2 (RS)-5-iodomethyl-1-(4-methoxyphenyl)pyrrolidin-2-one 
• 180629-38-3 (RS)-5-cyanomethyl-1-(4-methoxyphenyl)pyrrolidin-2-one 
• 180629-10-1 1-(4-Methoxy-phenyl)-5-(2H-tetrazol-5-ylmethyl)-pyrrolidin-2-one 
• 180629-36-1 Methanesulfonic acid 1-(4-methoxy-phenyl)-5-oxo-pyrrolidin-2-ylmethyl ester 
• 180629-28-1 1-(4-Methoxy-phenyl)-5-(2-methyl-2H-tetrazol-5-ylmethyl)-pyrrolidin-2-one 

Relevant articles and documents

Preparation and Diels-Alder Reactions of 1,1-Dicarbonylalkanes

1,1-Dicarbonyl- (ester, ketone, lactone) substituted alkenes are prepared from the corresponding saturated 1-phenylsulfinyl derivatives.These are formed from precursor sulfides, which can be efficiently prepared either by oxidation of β-hydroxy-α-phenylsulfenylcarbonyl compounds or direct acylation of α-phenylsulfenyl enolate anions with acid chlorides.Some of the title compounds can be isolated and then reacted while others are generated and reacted in situ in a Diels-Alder fashion with cyclopentadiene.Endo-exo selectivities are discussed.