76014-80-7 Usage
Description
4-oxo-4-(3-pyridinebutanal) is a member of the class of butanals, specifically succinic semialdehyde in which the hydroxy group of the carboxylic acid function is replaced by a pyridin-3-yl group. It is characterized as a yellow oil and is known to be unstable, with a limited shelf life of no more than six months.
Uses
Used in Research Applications:
4-oxo-4-(3-pyridinebutanal) is used as a research compound for studying its properties and potential applications in various fields. As a metabolite of the tobacco-specific nitrosamine, NNK (Cat. #M32575), it plays a significant role in understanding the chemical processes and effects related to tobacco consumption.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-oxo-4-(3-pyridinebutanal) may be used as a starting material or intermediate in the synthesis of various drugs or drug candidates. Its unique chemical structure could potentially be exploited to develop new therapeutic agents.
Used in Chemical Synthesis:
4-oxo-4-(3-pyridinebutanal) can be used as a chemical intermediate in the synthesis of various organic compounds, particularly those with potential applications in the pharmaceutical, agrochemical, or materials science industries.
Check Digit Verification of cas no
The CAS Registry Mumber 76014-80-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,0,1 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 76014-80:
(7*7)+(6*6)+(5*0)+(4*1)+(3*4)+(2*8)+(1*0)=117
117 % 10 = 7
So 76014-80-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NO2/c11-6-2-4-9(12)8-3-1-5-10-7-8/h1,3,5-7H,2,4H2
76014-80-7Relevant articles and documents
Methods of using QIAPINE
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Page/Page column 7, (2017/06/30)
Uses of QIAPINE? to treat internal bleeding, such as subdural hematoma and subarachinoid hemorrhage, and ocular bleeding, such as such as hyphema and vitreous hemorrhage, in a subject are described. Also described are uses of QIAPINE? to treat vision loss resulting from hyphema or vitreous hemorrhage.
Synthesis of nornicotine, nicotine and other functionalised derivatives using solid-supported reagents and scavengers
Baxendale, Ian R.,Brusotti, Gloria,Matsuoka, Masato,Ley, Steven V.
, p. 143 - 154 (2007/10/03)
The sequential use of solid-supported reagents and scavengers has led to an efficient synthesis of the natural products nornicotine 1, nicotine 2 and further fuctionalised derivatives. Also reported is a diastereoselective route to both enantiomers of nicotine 2.
A novel reductive aminocyclization for the syntheses of chiral pyrrolidines: Stereoselective syntheses of (S)-nornicotine and 2-(2'-pyrrolidyl)-pyridines
Loh, Teck-Peng,Zhou, Jian-Rong,Li, Xu-Ran,Sim, Keng-Yeow
, p. 7847 - 7850 (2007/10/03)
(S)-Nornicotine 2 was synthesized in four steps. A key step in the synthesis involved reductive aminocyclization of a 1,4-ketoaldehyde with 2,3,4,6-tetra-O-pivaloyl-β-D-galactosylamine 1 in the presence of sodium cyanoborohydride, diastereoselectively affording the corresponding stereoisomer 6 in 45% yield. The aminosugar moiety could be easily removed by acidic hydrolysis to furnish 2. The aminocyclization was further extended to asymmetric syntheses of novel chiral 2-(2'-pyrrolidyl)-pyridine ligands 12 and 13.