76049-48-4

Basic information

• Product Name: Methanone, (5-chloro-2-iodophenyl)phenyl-
• CAS NO: 76049-48-4
• Molecular Formula: C13H8ClIO
• Molecular Weight: 342.563
• Mol File: 76049-48-4.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Methanone, (5-chloro-2-iodophenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (5-chloro-2-iodophenyl)phenyl-(76049-48-4)
• EPA Substance Registry System: Methanone, (5-chloro-2-iodophenyl)phenyl-(76049-48-4)

Safety Data

• Hazardous Substances Data: 76049-48-4(Hazardous Substances Data)

Upstream product

• 13755-29-8 sodium tetrafluoroborate 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 635-21-2 5-chloroanthranilic acid 
• 4743-17-3 5-Chloroisatoic anhydride 
• 108-86-1 bromobenzene 
• 150879-48-4 N-methyl-N-methyloxy-2-amino-5-chlorobenzamide 

Downstream Products

• 76049-52-0 1-[4-chloro-2-benzoylphenyl]-3-phthalimidopropyne 
• 81078-22-0 8-chloro-1-phenyl-3H-2-benzazepine 
• 76049-61-1 3-amino-1-[4-chloro-2-benzoylphenyl]propyne 

Relevant articles and documents

One-Pot Synthesis of Spirocyclopenta[ a]indene Derivatives via a Cascade Ring Expansion and Intramolecular Friedel-Crafts-Type Cyclization

A one-pot efficient synthetic approach for the rapid construction of spirocyclopenta[a]indene derivatives has been developed via an iodine-initiated cascade ring expansion and intramolecular Friedel-Crafts-type cyclization from propargyl alcohol-tethered alkylidenecyclobutanes under mild conditions with broad substrate scope. This cascade process can be elegantly conducted on a gram scale. A plausible reaction mechanism has been proposed on the basis of a series of deuterium labeling and control experiments.

Palladium-Catalyzed Cascade Reductive and Carbonylative Cyclization of Ortho-Iodo-Tethered Methylenecyclopropanes (MCPs) Using N-Formylsaccharin as CO Source

A palladium-catalyzed reductive and carbonylative cyclization of ortho-iodo-tethered methylenecyclopropanes (MCPs) using N-formylsaccharin as CO source has been developed, affording the desired indanone derivatives in moderate to good yields with high regio- and stereoselectivity and good functional group compatibility.

3H-2-Benzazepines

There is presented 3H-2-benzazepines and 4,5-dihydro-3H-2-benzazepines of the formula STR1 wherein X is hydrogen, chloro or bromo, Y is hydrogen, fluoro or chloro with the proviso that X and Y cannot both be hydrogen and R1 is selected from the