76053-45-7Relevant articles and documents
Synthesis and anticancer activity of mitotic-specific 3,4-dihydropyridine-2(1h)-thiones
Peru?yńska, Magdalena,Borzyszkowska-Ledwig, Aleksandra,So?nicki, Jacek G.,Struk, ?ukasz,Idzik, Tomasz J.,Maciejewska, Gabriela,Skalski, ?ukasz,Piotrowska, Katarzyna,?ukasik, Pawe?,Dro?dzik, Marek,Kurzawski, Mateusz
, p. 1 - 36 (2021/03/03)
Most anticancer drugs target mitosis as the most crucial and fragile period of rapidly dividing cancer cells. However the limitations of classical chemotherapeutics drive the search for new more effective and selective compounds. For this purpose structur
HETEROCYCLIC COMPOUND AND USE THEREOF
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Paragraph 0697; 0698, (2013/06/05)
The present invention aims to provide a compound having a PDE inhibitory action and useful as a medicament for the prophylaxis or treatment of schizophrenia and the like. A compound represented by the formula (1x): wherein each symbol is as des
NOVEL DXR INHIBITORS FOR ANTIMICROBIAL THERAPY
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Page/Page column 68; 75, (2011/05/05)
The present invention generally concerns particular methods and compositions for antimicrobial therapy. In particuarl embodiments, the compositions target DXR. In specific embodiments, the compositions are electron-deficient heterocyclic rings.