762-51-6 Usage
Description
1-Fluoro-2-iodoethane is an organic compound that consists of a two-carbon chain with a fluorine atom attached to the first carbon and an iodine atom attached to the second carbon. It is a valuable intermediate in the synthesis of various organic compounds due to its unique structure and reactivity.
Uses
Used in Pharmaceutical Industry:
1-Fluoro-2-iodoethane is used as a reagent in the organic synthesis of several compounds, including the synthesis of fluorinated U-50488 analogs. These analogs serve as PET (positron emission tomography) tracers for studying kappa opioid receptors, which play a crucial role in pain modulation and addiction.
Used in Neuroimaging:
1-Fluoro-2-iodoethane is also utilized in the synthesis of MK-3168, an imidazole analog that functions as a PET tracer. This tracer is specifically designed for the imaging of brain fatty acid amide hydrolase (FAAH), an enzyme involved in the degradation of endocannabinoids. The imaging of FAAH can provide valuable insights into various neurological disorders and the endocannabinoid system's role in them.
Check Digit Verification of cas no
The CAS Registry Mumber 762-51-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,6 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 762-51:
(5*7)+(4*6)+(3*2)+(2*5)+(1*1)=76
76 % 10 = 6
So 762-51-6 is a valid CAS Registry Number.
InChI:InChI=1/C2H4FI/c3-1-2-4/h1-2H2
762-51-6Relevant articles and documents
SELECTIVE LIGANDS FOR TAU AGGREGATES
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Page/Page column 124, (2021/04/23)
The present invention provides a compound of formula (I) and compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt, ester, amide or carbamate thereof, or a salt of such an ester, amide or carbamate. The present invention also provides a compound of formula (X) and compositions comprising a compound of formula (X) or a pharmaceutically acceptable salt, ester, amide or carbamate thereof, or a salt of such an ester, amide or carbamate. The present invention further provides uses of the compounds of formula (I) and (X) and compositions comprising compounds of formula (I) and (X), including the use of such compounds and compositions for the diagnosis and treatment of neurodegenerative diseases, and especially tauopathies such as Alzheimer′s disease.
