762269-31-8

Basic information

• Product Name: 2H-1,2-Oxazine-4,4-dimethanol, tetrahydro-2-phenyl-3-(2-thienyl)-
• CAS NO: 762269-31-8
• Molecular Formula: C16H19NO3S
• Molecular Weight: 305.398
• Mol File: 762269-31-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-1,2-Oxazine-4,4-dimethanol, tetrahydro-2-phenyl-3-(2-thienyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,2-Oxazine-4,4-dimethanol, tetrahydro-2-phenyl-3-(2-thienyl)-(762269-31-8)
• EPA Substance Registry System: 2H-1,2-Oxazine-4,4-dimethanol, tetrahydro-2-phenyl-3-(2-thienyl)-(762269-31-8)

Safety Data

• Hazardous Substances Data: 762269-31-8(Hazardous Substances Data)

Upstream product

• 6914-71-2 dimethyl 1,1-cyclopropanedicarboxylate 
• 100-65-2 N-Phenylhydroxylamine 
• 848587-08-6 2-phenyl-3-thiophen-2-yl-[1,2]oxazinane-4,4-dicarboxylic acid dimethyl ester 

Downstream Products

• 762269-35-2 9,9-dimethyl-2-phenyl-1-thiophen-2-yl-3,8,10-trioxa-2-aza-spiro[5.5]undecane 

Relevant articles and documents

Diastereoselective synthesis of pyrrolidines using a nitrone/cyclopropane cycloaddition: Synthesis of the tetracyclic core of nakadomarin A

(Chemical Equation Presented) The synthesis of the tetracyclic core of nakadomarin A is described. The core contains all the heterocycles and the required stereocenters found in the natural product and provides a promising route to the target itself. The strategy utilizes a general, diastereoselective pyrrolidine synthesis that proceeds via a homo 3 + 2 dipolar cycloaddition. The scope of this methodology is also described.