762275-75-2Relevant articles and documents
Substituted 6-phenyl-pyridin-2-ylamines: Selective and potent inhibitors of neuronal nitric oxide synthase
Nason, Deane M.,Heck, Steven D.,Bodenstein, Mathew S.,Lowe III, John A.,Nelson, Robert B.,Liston, Dane R.,Nolan, Charles E.,Lanyon, Lorraine F.,Ward, Karen M.,Volkmann, Robert A.
, p. 4511 - 4514 (2007/10/03)
The synthesis and nNOS and eNOS activity of 6-(4-(dimethylaminoalkyl)-/6- (4-(dimethylaminoalkoxy)-5-ethyl-2-methoxyphenyl)-pyridin-2-ylamines and 6-(4-(dimethylaminoalkyl)-/6-(4-(dimethylaminoalkoxy)-2,5-dimethoxyphenyl) -pyridin-2-ylamines 1-8 are described. These compounds are potent inhibitors of the human nNOS isoform.