7632-10-2Relevant articles and documents
Compositions and Methods for Treating Cocaine, Nicotine, and Methamphetamine Dependence
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Page/Page column 5/7, (2021/12/08)
This invention provides a composition of matter comprising a plurality of cocaine-succinyl-BSA, wherein the average ratio of cocaine-succinyl moieties to BSA is at least 7.0. This invention also provides a composition of matter comprising a plurality of nicotine-5-succinyl-BSA, wherein the average ratio of nicotine-5-succinyl moieties to BSA is at least 7.0. This invention further provides a composition of matter comprising a plurality of methamphetamine-5-succinyl-BSA, wherein the average ratio of methamphetamine-5-succinyl moieties to BSA is at least 7.0. This invention still further provides related pharmaceutical compositions, therapeutic methods, prophylactic methods, synthetic methods, and articles of manufacture.
Hydrogen activation by 2-boryl-N,N-dialkylanilines: A revision of Piers' ansa-aminoborane
Chernichenko, Konstantin,Nieger, Martin,Leskelae, Markku,Repo, Timo
supporting information; experimental part, p. 9029 - 9032 (2012/09/08)
Two 2-[bis(pentafluorophenyl)boryl]-N,N-dialkylanilines reported here exemplify a new class of intramolecular frustrated B/N Lewis pairs. A structure closely related to this class structure was synthesized in 2003 by Piers et al. but was unable to activate H2. The new aminoboranes can activate hydrogen at near ambient conditions; besides, one of them can hydrogenate imines and enamines in a catalytic fashion demonstrating the validity of the original Piers' approach to hydrogen activation with ansa-aminoboranes.
Synthesis of 2-Arylethylamines by the Curtius Rearrangement
Schulze, Matthias
experimental part, p. 1461 - 1476 (2010/07/08)
2-Arylethylamine derivatives were synthesized using the Curtius reaction and with three different methods of preparing the acyl azide functional group. Carbamates derived from isocyanate were convenient protecting groups for alkylation of amines. Starting from benzaldehyde, amphetamine was prepared in three steps through an oxazolidin-2-one intermediate in 62% overall yield. Copyright Taylor & Francis Group, LLC.