76594-51-9Relevant articles and documents
Regio- and Enantioselective Copper-Catalyzed 1,4-Conjugate Addition of Trimethylaluminium to Linear α,β,γ,δ-Unsaturated Alkyl Ketones
Wu, Xiaoting,Xie, Fang,Ling, Zheng,Tang, Liang,Zhang, Wanbin
, p. 2510 - 2518 (2016)
A regio- and enantioselective copper-catalyzed 1,4-conjugate addition of trimethylaluminium to linear δ-aryl-substituted α,β,γ,δ-unsaturated alkyl ketones was developed. A series of γ,δ-unsaturated alkyl ketones were obtained in good yields with high regio- and enantioselectivity (up to 88% ee and 96:4 dr). Expansion of the reaction scope to substrates containing aromatic heterocycles also afforded good yields and enantioselectivities (up to 91% ee) with very high regioselectivities, exclusively providing the single 1,4-products. (Figure presented.).
Unsaturated Oximes, XXIV: 6-Phenyl-3,5-hexadien-2-ones, 7-Phenyl-4,6-heptadien-3-ones and Their Oximes
Unterhalt, Bernard,Weyrich, Klaus
, p. 913 - 918 (2007/10/02)
Substituted cinnamyl aldehydes are condensed with acetone and butanone.The structures of the resulting unsaturated ketones and their oximes are discussed.
