76618-48-9 Usage
Chemical structure
A chalcone derivative with a propanone backbone, phenyl group, and phenylselanyl group attached.
Potential applications
Medicinal chemistry, specifically in the development of new drugs and pharmaceuticals.
Phenylselanyl group
Of interest due to its potential biological and pharmacological activities.
Usage
As a building block for the synthesis of novel organic molecules with therapeutic properties.
Research value
Valuable target for further research in drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 76618-48-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,6,1 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 76618-48:
(7*7)+(6*6)+(5*6)+(4*1)+(3*8)+(2*4)+(1*8)=159
159 % 10 = 9
So 76618-48-9 is a valid CAS Registry Number.
76618-48-9Relevant articles and documents
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Gilman,Cason
, p. 1074 (1951)
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Ceric ammonium nitrate (CAN) as a green and highly efficient promoter for the 1,4-addition of thiols and benzeneselenol to α,β-unsaturated ketones
Chu, Cheng-Ming,Gao, Shijay,Sastry,Kuo, Chun-Wei,Lu, Chaowei,Liu, Ju-Tsung,Yao, Ching-Fa
, p. 1863 - 1871 (2007/10/03)
A mild and efficient process for the 1,4-addition of thiols and benzeneselenols to various α,β-unsaturated ketones using a catalytic amount of CAN with excellent product yields is described. This inexpensive, nontoxic, and readily available catalytic ceric(IV) ammonium nitrate system efficiently catalyzes conjugate addition reactions between thiol derivatives and various α,β-unsaturated ketones under solvent-free conditions. A plausible mechanism for the role of CAN, both as a promoter in free radical chain addition reactions as well as a catalyst for the conjugate addition process is proposed.
