76647-67-1 Usage
General Description
(2S,3R)-3-Amino-2-hydroxy-4-phenyl-butyric acid is a chemical compound with the molecular formula C10H13NO3. It is a chiral amino acid derivative that contains an amino group and a hydroxyl group on a four-carbon chain with a phenyl group attached. It is an important intermediate in the synthesis of various pharmaceuticals and natural products, and it plays a role in the biosynthesis of certain peptides. (2S,3R)-3-AMINO-2-HYDROXY-4-PHENYL-BUTYRIC ACID has potential applications in the development of new drugs and biologically active molecules due to its unique structural properties and functional groups. Additionally, it may have potential bioactive properties and is the subject of ongoing research in the fields of medicinal chemistry and chemical biology.
Check Digit Verification of cas no
The CAS Registry Mumber 76647-67-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,6,4 and 7 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 76647-67:
(7*7)+(6*6)+(5*6)+(4*4)+(3*7)+(2*6)+(1*7)=171
171 % 10 = 1
So 76647-67-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO3/c11-8(9(12)10(13)14)6-7-4-2-1-3-5-7/h1-5,8-9,12H,6,11H2,(H,13,14)/t8-,9+/m0/s1
76647-67-1Relevant articles and documents
N -Boc amines to oxazolidinones via Pd(II)/bis-sulfoxide/br?nsted acid Co-catalyzed allylic C-H oxidation
Osberger, Thomas J.,White, M. Christina
, p. 11176 - 11181 (2014/08/18)
A Pd(II)/bis-sulfoxide/Br?nsted acid catalyzed allylic C-H oxidation reaction for the synthesis of oxazolidinones from simple N-Boc amines is reported. A range of oxazolidinones are furnished in good yields (avg 63%) and excellent diastereoselectivities (avg 15:1) to furnish products regioisomeric from those previously obtained using allylic C-H amination reactions. Mechanistic studies suggest the role of the phosphoric acid is to furnish a Pd(II)bis-sulfoxide phosphate catalyst that promotes allylic C-H cleavage and π-allylPd functionalization with a weak, aprotic oxygen nucleophile and to assist in catalyst regeneration.
Regio- and stereo-specific synthesis of threo-3-amino-2-hydroxy-acids, novel amino-acids contained in aminopeptidase inhibitors of microbial origin.
Kato,Saino,Nishizawa,Takita,Umezawa
, p. 1618 - 1621 (2007/10/02)
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